April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Relationship between macular microstructure and visual acuity after cataract surgery in patients with retinitis pigmentosa
Author Affiliations & Notes
  • Ken Kumagai
    Ophthalmology, Chiba University, Chiba, Japan
  • Yosuke Nakamura
    Ophthalmology, Chiba University, Chiba, Japan
  • Akira Hagiwaraa
    Ophthalmology, Chiba University, Chiba, Japan
  • Shuichi Yamamoto
    Ophthalmology, Chiba University, Chiba, Japan
  • Footnotes
    Commercial Relationships Ken Kumagai, None; Yosuke Nakamura, None; Akira Hagiwaraa, None; Shuichi Yamamoto, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 1410. doi:
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      Ken Kumagai, Yosuke Nakamura, Akira Hagiwaraa, Shuichi Yamamoto; Relationship between macular microstructure and visual acuity after cataract surgery in patients with retinitis pigmentosa. Invest. Ophthalmol. Vis. Sci. 2014;55(13):1410.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To study the relationship between the macular microstructure measured by optical coherence tomography (OCT) and visual acuity after cataract surgery in patients with retinitis pigmentosa (RP).

Methods: Thirty-six eyes of 29 consecutive RP patients who underwent cataract surgery at the Chiba University Hospital were studied. The best-corrected visual acuity (BCVA) was measured before and 3 months after the surgery. The foveal thickness (FT) and the length of junction between inner and outer segments of photoreceptors (IS/OS) were measured by spectral-domain OCT. The appearance of the IS/OS junction in the OCT images at the fovea was graded: Grade 1, IS/OS not visible; Grade 2, abnormal or discontinuous IS/OS; and Grade 3, normal IS/OS.

Results: The mean BCVA was improved significantly from 0.81±0.45 in logMAR units at baseline to 0.35±0.47 in logMAR units at 3 months after surgery (P <0.0001). There was no significant correlation between the postoperative BCVA and the length of the IS/OS (r= -0.102, P =0.70), but a significant correlation was found between the postoperative BCVA and FT (r =0.47, P =0.0006). Eyes with Grade 2 IS/OS and Grade 3 IS/OS had significant improvements of the postoperatively BCVA (P =0.0077 and P=0.0003, respectively), while those with Grade 1 IS/OS did not have a significant change (P =0.063). The postoperative BCVA increase was significantly greater in eyes with Grade 3 IS/OS than those with Grade 1 and Grade 2 IS/OS (P=0.0003 and P<0.0001, respectively).

Conclusions: The presence of normal IS/OS junction in the OCT images is associated with good visual recovery after cataract surgery in RP patients. The state of the IS/OS may be a crucial factor for predicting the postoperative visual acuity.

Keywords: 696 retinal degenerations: hereditary • 445 cataract  
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