April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
The Effect of Corneal Biomechanical Properties on Rebound Tonometer in Patients with Normal Tension Glaucoma
Author Affiliations & Notes
  • Jong-Hoon Shin
    Ophthalmology, Pusan National University Hospital, Busan, Republic of Korea
  • Jiwoong Lee
    Ophthalmology, Pusan National University Hospital, Busan, Republic of Korea
    Ophthalmology, The Jules Stein Eye Institute, University of California at Los Angeles School of Medicine, Los Angeles, CA
  • Eun Ah Kim
    Ophthalmology, Chung Hwa Sun Eye Clinic, Daegu, Republic of Korea
  • Joseph Caprioli
    Ophthalmology, The Jules Stein Eye Institute, University of California at Los Angeles School of Medicine, Los Angeles, CA
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 145. doi:
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      Jong-Hoon Shin, Jiwoong Lee, Eun Ah Kim, Joseph Caprioli; The Effect of Corneal Biomechanical Properties on Rebound Tonometer in Patients with Normal Tension Glaucoma. Invest. Ophthalmol. Vis. Sci. 2014;55(13):145.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To evaluate the effects of corneal biomechanical properties on intraocular pressure (IOP) measurements with ICare and to compare IOP measurements with ICare, ORA and GAT in patients with normal tension glaucoma (NTG)

Methods: IOP was measured in both NTG patients and normal subjects with ICare, Ocular response analyzer (ORA), and Goldmann applanation tonometry (GAT) by a single observer. All subjects had corneal hysteresis (CH) and corenal resistance factor (CRF) measurements which were obtained with ORA, central corneal thickness (CCT), axial length (AXL), spherical equivalent (SE), and corneal curvature (K).

Results: This study enrolled ninety-seven eyes of ninety-seven patients with NTG and eighty-nine eyes of eighty-nine normal subjects.CCT, CH and CRF in NTG patients were significantly lower than in normal subjects (P = 0.033, 0.006, 0.003, respectively). In both NTG and normal control, IOP readings with ICare were not significantly different with IOPcc, IOPg and GAT. There was no significant difference in IOP levels with ICare, IOPcc, IOPg, and GAT between two groups. However, the difference between ICare readings and IOPcc in NTG patients was significantly higher than in normal subjects (P = 0.018). In multiple regression analysis, CH and CRF were significantly associated with IOP measurements with ICare in NTG patients and normal subjects (P<0.001, adjusted R2= 0.580, P<0.001, adjusted R2= 0.534, respectively). In the Bland-Altman plot comparing agreements between two IOP parameters, there was reasonable agreement in both groups.

Conclusions: Since ICare is a convenient way to measure IOP, ICare is a reasonable option as an alternative tonometer in NTG. However, the clinician must consider that differenct corneal biomechanical factors in NTG patients can cause ICare to underestimate IOP.

Keywords: 568 intraocular pressure  
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