April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Effect of Novel Architecture for Femtosecond Laser Astigmatic Keratotomy on Induced Aberration on Patient-Specific Computational Modeling
Author Affiliations & Notes
  • Anita Nevyas-Wallace
    Nevyas Eye Associates, Bala Cynwyd, PA
  • Harald P Studer
    Integrated Scientific Services, Port, Switzerland
  • Cynthia J Roberts
    Ophthalmology, The Ohio State University, Columbus, OH
    Biomedical Engineering, The Ohio State University, Columbus, OH
  • Footnotes
    Commercial Relationships Anita Nevyas-Wallace, Bausch + Lomb (C), EyeIC (I), Patent application number 13/402,389 (P), Varitronics, Inc. (I); Harald Studer, ISS Integrated Scientific Services AG (E); Cynthia Roberts, Carl Zeiss Meditec: (F), Oculus (C), Sooft Italia: (R), Ziemer (C)
  • Footnotes
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Investigative Ophthalmology & Visual Science April 2014, Vol.55, 1553. doi:
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    • Get Citation

      Anita Nevyas-Wallace, Harald P Studer, Cynthia J Roberts; Effect of Novel Architecture for Femtosecond Laser Astigmatic Keratotomy on Induced Aberration on Patient-Specific Computational Modeling. Invest. Ophthalmol. Vis. Sci. 2014;55(13):1553.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To compare novel astigmatic keratotomy (AK) incision architectures to standard AK using patient-specific computational modeling to evaluate astigmatic effect and induction of higher order aberrations (HOA)

 
Methods
 

Finite element modeling (Optimeyes) was used to perform simulations of femtosecond (FS) laser arcuate corneal relaxing incisions on patient-specific corneal models. Modeling (previously validated clinically) accounted for corneal stroma being denser anteriorly than posteriorly. Simulations of AK incisions of uniform depth and thickness were compared with those of AK incisions whose ends were either deeper, thicker, or both deeper and thicker than the center of the incision. Astigmatic effect and induced higher order aberration were assessed for incisions 30 degrees in length made at the 8mm optical zone.

 
Results
 

Compared with incisions of uniform depth and thickness, shallow center incisions achieved 13% greater astigmatic effect, and diminished induced HOA: spherical aberration by 26%, coma by 21%, trefoil by 100%, and tetrafoil by 3%. Uniform depth incisions with thicker ends achieved 1% greater astigmatic effect, and diminished induced spherical aberration by 18%, coma by 74%, trefoil by 99%, and increased tetrafoil by 17%. The thicker ends with shallower center incisions achieved 15% greater astigmatic effect, and diminished induced HOA: spherical aberration by 20%, coma by 82%, trefoil by 81%, and tetrafoil by 20%.

 
Conclusions
 

Novel FS laser AK incisions with thicker ends and shallower center produced optimal results with greatest astigmatic effect and least induction of HOA. All novel architectures generated greater astigmatic effect and less induced HOA than traditional. Control of incision architecture may aid in optimizing vision in FS laser AK.

 
 
All combinations of Thicker Ends Shallow Center show Reduced Coma compared to traditional corneal relaxing incision
 
All combinations of Thicker Ends Shallow Center show Reduced Coma compared to traditional corneal relaxing incision
 
 
Some combinations of Thicker Ends Shallow Center show Greater Astigmatic Correction compared to traditional incision, even though they induce less HOA
 
Some combinations of Thicker Ends Shallow Center show Greater Astigmatic Correction compared to traditional incision, even though they induce less HOA
 
Keywords: 428 astigmatism • 678 refractive surgery • 578 laser  
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