April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Wide Field MHz OCT imaging of the vitreoretinal interface
Author Affiliations & Notes
  • Karsten Ulrich Kortuem
    Ophthalmology, Ludwig-Maximilians-University, Munich, Germany
  • Jan Philip Kolb
    Institute for Biomolecular Optics, Faculty of Physics, Ludwig-Maximilians-University, Munich, Germany
  • Thomas Klein
    Institute for Biomolecular Optics, Faculty of Physics, Ludwig-Maximilians-University, Munich, Germany
  • Kathrin Mohler
    Institute for Biomolecular Optics, Faculty of Physics, Ludwig-Maximilians-University, Munich, Germany
  • Anselm Kampik
    Ophthalmology, Ludwig-Maximilians-University, Munich, Germany
  • Aljoscha S Neubauer
    Ophthalmology, Ludwig-Maximilians-University, Munich, Germany
  • Wolfgang Wieser
    Institute for Biomolecular Optics, Faculty of Physics, Ludwig-Maximilians-University, Munich, Germany
  • Robert Huber
    Institute for Biomolecular Optics, Faculty of Physics, Ludwig-Maximilians-University, Munich, Germany
    Institute of Biomedical Optics, Universität zu Lübeck, Lubeck, Germany
  • Christos Haritoglou
    Ophthalmology, Ludwig-Maximilians-University, Munich, Germany
  • Footnotes
    Commercial Relationships Karsten Kortuem, None; Jan Philip Kolb, None; Thomas Klein, None; Kathrin Mohler, None; Anselm Kampik, None; Aljoscha Neubauer, None; Wolfgang Wieser, None; Robert Huber, None; Christos Haritoglou, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 1619. doi:
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      Karsten Ulrich Kortuem, Jan Philip Kolb, Thomas Klein, Kathrin Mohler, Anselm Kampik, Aljoscha S Neubauer, Wolfgang Wieser, Robert Huber, Christos Haritoglou; Wide Field MHz OCT imaging of the vitreoretinal interface. Invest. Ophthalmol. Vis. Sci. 2014;55(13):1619.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To investigate changes caused by vitreoretinal interface disease with a multi-MHz OCT over a wide field of view of 60°.

 
Methods
 

We used custom swept-source OCT device with a 1060nm Fourier-domain mode-locked laser source achieving a line rate of 1.68MHz. Within 1.82s datasets consisting of 2088x1024 A-scans over 60° were acquired from 5 patients with vitreoretinal traction due to VMTS and 3 patients with vascular pathology. The densely sampled three dimensional datasets were investigated in B-Scan cross-sections as well as en-face images and 3D reconstructions.

 
Results
 

Vitreoretinal traction could be imaged well in most of the cases, although the current sensitivity of the system limited image quality. Across the whole 60° field of view in the OCT datasets vitreoretinal tractions could be topographically assessed, always including the macula and optic disc, where vitreous anchorage could be shown. By means of the depth-scans as part of the 3D OCT volume we could image traction-associated retinal changes such as retinal elevation or RPE detachment.

 
Conclusions
 

This unique three dimensional visualization of the retina over 60° field of view with a MHz OCT is feasible in patients with vitreoretinal interface disease and might offer additional clinical insights on the three-dimensional topology of tractional changes.

 
 
Three dimensional Wide Field MHz OCT retinal and vitreous visualization.
 
Three dimensional Wide Field MHz OCT retinal and vitreous visualization.
 
Keywords: 552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • 550 imaging/image analysis: clinical • 692 retinal adhesion  
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