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Karsten Ulrich Kortuem, Jan Philip Kolb, Thomas Klein, Kathrin Mohler, Anselm Kampik, Aljoscha S Neubauer, Wolfgang Wieser, Robert Huber, Christos Haritoglou; Wide Field MHz OCT imaging of the vitreoretinal interface. Invest. Ophthalmol. Vis. Sci. 2014;55(13):1619.
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To investigate changes caused by vitreoretinal interface disease with a multi-MHz OCT over a wide field of view of 60°.
We used custom swept-source OCT device with a 1060nm Fourier-domain mode-locked laser source achieving a line rate of 1.68MHz. Within 1.82s datasets consisting of 2088x1024 A-scans over 60° were acquired from 5 patients with vitreoretinal traction due to VMTS and 3 patients with vascular pathology. The densely sampled three dimensional datasets were investigated in B-Scan cross-sections as well as en-face images and 3D reconstructions.
Vitreoretinal traction could be imaged well in most of the cases, although the current sensitivity of the system limited image quality. Across the whole 60° field of view in the OCT datasets vitreoretinal tractions could be topographically assessed, always including the macula and optic disc, where vitreous anchorage could be shown. By means of the depth-scans as part of the 3D OCT volume we could image traction-associated retinal changes such as retinal elevation or RPE detachment.
This unique three dimensional visualization of the retina over 60° field of view with a MHz OCT is feasible in patients with vitreoretinal interface disease and might offer additional clinical insights on the three-dimensional topology of tractional changes.
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