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Salvador Pastor, Maria Gil Martinez, Stephen Charles, Susmito Biswas, David Barry Henson, David McLeod, Paulo E Stanga; Swept-Source Optical Coherence Tomography Assessment of the Cortical Vitreous and Choroidal Thickness in Different Macular Disorders. Invest. Ophthalmol. Vis. Sci. 2014;55(13):1621.
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Swept-Source Optical Coherence Tomography (SS-OCT) determination of the prevalence of the Bursa Premacularis (BPM) and Space of Martegiani (SM) and assessment of Choroidal Thickness (CT) in healthy eyes (HE) and in eyes with various macular disorders (MD).
Retrospective, comparative and non-interventional study. One hundred and thirteen (113) consecutive patients underwent 1,050nm SS-OCT (Atlantis DRI-OCT1®, Topcon Corp, Japan). The prevalence of the BPM and SM was assessed in HE and MD. Macular CT was determined by measuring the distance between the RPE and the choroid/sclera junction at three sites along a 500µm line centred on the fovea of 53 HE and 138 MD. Patients were categorised into 8 groups; Diabetic Retinopathy (DR) (19), Cystoid Macular Oedema (CMO) (26), Age-Related Macular Degeneration (AMD) (32), High Myopia (HM) (22), Vitreomacular Adhesion (VMA) and/or Epiretinal Membrane (ERM) (11), Central Serous Retinopathy (CSR) (9), Retinitis Pigmentosa (RP) (9) and Miscellaneous (10).
Mean age was 47±23 years for HE versus 57±22 years for MD (p<0.05 U Mann Whitney). Mean CT was 251±93μm for HE versus 218±104μm for MD (p=0.041 U Mann Whitney). BPM was present in 66% of HE (35) versus 31.9% of MD (44) (p<0.05 Fisher’s test). SM was present in 54.7% of HE (29) versus 32.6% of MD (43) (p<0.004 Fisher’s test). Sub-group analysis showed significant differences in CT between HE and MD with AMD, HM, VMA and/or ERM, CSR and RP (p<0.05 U Mann Whitney).
SS-OCT allows the measurement of CT in different macular pathologies and the assessment of the cortical vitreous and prevalence of the BPM and SM. The BPM and SM were more prevalent in HE. A thin choroid may be associated with the AMD, High Myopia, VMA and ERM groups and a thick one with the CSR group.
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