April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Incidence of rhegmatogenous retinal detachments following intravitreal injections
Harry Dang; Rajeev H Muni; Robert G Devenyi; Wai-Ching Lam; Kenneth Eng; Carol E Schwartz; Radha P Kohly; Peter J Kertes
Author Affiliations & Notes
  • Harry Dang
    Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
    Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada
  • Rajeev H Muni
    Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
    St. Michael's Hospital, Toronto, ON, Canada
  • Robert G Devenyi
    Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
    Toronto Western Hospital, University Health Network, Toronto, ON, Canada
  • Wai-Ching Lam
    Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
    Toronto Western Hospital, University Health Network, Toronto, ON, Canada
  • Kenneth Eng
    Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
    Sunnybrook Health Sciences Centre, Toronto, ON, Canada
  • Carol E Schwartz
    Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
    Sunnybrook Health Sciences Centre, Toronto, ON, Canada
  • Radha P Kohly
    Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
    Sunnybrook Health Sciences Centre, Toronto, ON, Canada
  • Peter J Kertes
    Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
    Sunnybrook Health Sciences Centre, Toronto, ON, Canada
  • Footnotes
    Commercial Relationships Harry Dang, None; Rajeev Muni, None; Robert Devenyi, None; Wai-Ching Lam, None; Kenneth Eng, None; Carol Schwartz, None; Radha Kohly, None; Peter Kertes, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 2309. doi:
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      Harry Dang, Rajeev H Muni, Robert G Devenyi, Wai-Ching Lam, Kenneth Eng, Carol E Schwartz, Radha P Kohly, Peter J Kertes; Incidence of rhegmatogenous retinal detachments following intravitreal injections. Invest. Ophthalmol. Vis. Sci. 2014;55(13):2309.

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Abstract

Purpose: To report the incidence of rhegmatogenous retinal detachments (RRD) after intravitreal injections.

Methods: A multicentre, retrospective case series measured the incidence of RRD in patients receiving intravitreal injections. The number of injections was determined from billing code and electronic medical records from seven ophthalmology practices. The indications for injection included age-related macular degeneration, central and branch retinal vein occlusion, diabetic macular edema, and miscellaneous causes. The primary outcome measure was the incidence of RRD after intravitreal injection.

Results: A total of forty thousand three hundred twenty-two intravitreal injections were identified for 9525 patients between January 2000 and September 2013. The mean age of the cohort was 68.6 years (range 25-100) and the mean follow-up duration was 32.27 months (range 0-120.4). Of the 1708 patients reviewed (to date), 6 eyes of 6 patients with RRD after injection were reported. Time from first injection to RRD was a mean of 1.5 years (range 0.9 - 2.0). The overall incidence of RRD was 6 in 20294 (0.029% per injection).

Conclusions: The overall rate of intravitreal injection-related RRD is low (1 per 3382 injections).

Keywords: 697 retinal detachment • 561 injection • 688 retina  
© 2014, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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