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Harry Dang, Rajeev H Muni, Robert G Devenyi, Wai-Ching Lam, Kenneth Eng, Carol E Schwartz, Radha P Kohly, Peter J Kertes; Incidence of rhegmatogenous retinal detachments following intravitreal injections. Invest. Ophthalmol. Vis. Sci. 2014;55(13):2309.
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© ARVO (1962-2015); The Authors (2016-present)
To report the incidence of rhegmatogenous retinal detachments (RRD) after intravitreal injections.
A multicentre, retrospective case series measured the incidence of RRD in patients receiving intravitreal injections. The number of injections was determined from billing code and electronic medical records from seven ophthalmology practices. The indications for injection included age-related macular degeneration, central and branch retinal vein occlusion, diabetic macular edema, and miscellaneous causes. The primary outcome measure was the incidence of RRD after intravitreal injection.
A total of forty thousand three hundred twenty-two intravitreal injections were identified for 9525 patients between January 2000 and September 2013. The mean age of the cohort was 68.6 years (range 25-100) and the mean follow-up duration was 32.27 months (range 0-120.4). Of the 1708 patients reviewed (to date), 6 eyes of 6 patients with RRD after injection were reported. Time from first injection to RRD was a mean of 1.5 years (range 0.9 - 2.0). The overall incidence of RRD was 6 in 20294 (0.029% per injection).
The overall rate of intravitreal injection-related RRD is low (1 per 3382 injections).
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