April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Integrative Surgical Instrument Solutions for Optimizing Intraoperative OCT for Ophthalmic Surgery
Author Affiliations & Notes
  • Justis P Ehlers
    Ophthalmic Imaging Center Cole Eye Institute, Cleveland Clinic, Cleveland, OH
  • Sunil K Srivastava
    Ophthalmic Imaging Center Cole Eye Institute, Cleveland Clinic, Cleveland, OH
  • Yuji Itoh
    Ophthalmic Imaging Center Cole Eye Institute, Cleveland Clinic, Cleveland, OH
  • Yuankai K Tao
    Ophthalmic Imaging Center Cole Eye Institute, Cleveland Clinic, Cleveland, OH
  • Footnotes
    Commercial Relationships Justis Ehlers, Bioptigen (P), Regeneron (R), Thrombogenics (C), Thrombogenics (R); Sunil Srivastava, Alimera (C), Allergan (F), Bausch and Lomb (C), Bioptigen (P), Clearside (F), Novartis (F), Regeneron (C); Yuji Itoh, None; Yuankai Tao, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 2336. doi:
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    • Get Citation

      Justis P Ehlers, Sunil K Srivastava, Yuji Itoh, Yuankai K Tao; Integrative Surgical Instrument Solutions for Optimizing Intraoperative OCT for Ophthalmic Surgery. Invest. Ophthalmol. Vis. Sci. 2014;55(13):2336.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

Previous studies have also demonstrated the limitations of conventional metallic instruments for OCT-based visualization (e.g., shadowing of underlying tissue, poor instrument identification). Optimal integration into the surgical environment will require significant advances in surgical instrumentation to optimize OCT-based visualization of maneuvers utilizing a microscope integrated OCT (MIOCT) system. The purpose of this study was to assess novel surgical instrumentation prototypes specifically designed for use with a MIOCT system to assess OCT-based visualization of instrument-tissue interactions.

 
Methods
 

CT-compatible instrumentation, including vitreoretinal forceps and surgical picks, were prototyped based on optimal material properties for OCT transparency and contrast. MIOCT imaging was performed in fresh cadaveric porcine eyes using a second-generation MIOCT prototype system with enhanced ergonomic/functional features (FIGURE 1). Volumetric imaging and real-time OCT-based motion capture using custom imaging acquisition protocols were used for instrument/tissue visualization at numerous locations, including mid-vitreous and retinal surface.

 
Results
 

High-resolution MIOCT images allowed prototype instrument visualization at all locations. OCT-compatible surgical instruments exhibited excellent optical properties, including minimal shadowing and optimal light scattering. Minimizing shadowing provided outstanding views of the underlying tissue, increasing the capacity for instrument-tissue interaction visualization (FIGURE 2). The light scattering properties provided for excellent B-scan resolution of the instrument tip, compared to specular reflection artifacts often seen with metallic instruments. Motion capture and volumetric OCT scans were successfully obtained during surgical maneuvers.

 
Conclusions
 

Enhanced visualization of instrument/tissue interactions is possible utilizing a second generation MIOCT system in combination with OCT-friendly instrumentation. This represents an important achievement for improved integration of intraoperative OCT and the potential to fully integrate this technology into the ophthalmic operating room.

 
 
Microscope integrated OCT system
 
Microscope integrated OCT system
 
 
Figure 2: OCT-compatible surgical pick with 3D reconstruction and parallel/perpendicular B-scans at instrument tip revealing excellent visualization of underlying tissue and instrument tip.
 
Figure 2: OCT-compatible surgical pick with 3D reconstruction and parallel/perpendicular B-scans at instrument tip revealing excellent visualization of underlying tissue and instrument tip.
 
Keywords: 762 vitreoretinal surgery • 552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)  
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