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David Magana-García, Karina Ramos-Espinoza, Carlos Bonilla-Barraza, Efrain Romo-Garcia; Brilliant Blue G as an alternative to Trypan Blue for conducting continuous curvilinear capsulorhexis in cataract surgery. Invest. Ophthalmol. Vis. Sci. 2014;55(13):2537.
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To compare the use of Brilliant Blue G and Trypan Blue when performing lens capsule staning for cataract surgery
In this pilot study, patients diagnosed with cataract and no preexisting ocular pathology in age range of 40-80 years were randomized into 2 groups. Control group Blue Trypan 0.1% capsulorhexis assisted and study group Brilliant Blue G 0.025% assisted capsulorhexis, assessing the intensity of intraoperative staining and capsule manageability, corneal edema, IOP, VA, anterior
When comparing both groups, data show that Brilliant Blue G is as effective as Trypan Blue for staining the lens capsule and visualization during surgery; Surgeons found more stability and control when performing CCC, we didnt found statistically significant difference in VA, IOP, corneal edema or inflammation of the anterior chamber.
Brilliant Blue G is a highly biocompatible dye wich helps to perform safely capsulorhexis during phacoemulsification surgery. Lens capsule staining was similar to Trypan Blue group; Manage and control of CCC was higher when using Brilliant Blue G. Outcomes of surgery in terms of VA, IOP and anterior chamber inflammation were similar in both groups.
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