April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Comparison of Subfoveal Choroidal Thickness in Healthy Pregnancy and Preeclampsia
Author Affiliations & Notes
  • Yun Taek Kim
    Ophthalmology, Ewha Womans University, Seoul, Republic of Korea
  • Ji Won Kim
    Ophthalmology, Ewha Womans University, Seoul, Republic of Korea
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 257. doi:
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      Yun Taek Kim, Ji Won Kim; Comparison of Subfoveal Choroidal Thickness in Healthy Pregnancy and Preeclampsia. Invest. Ophthalmol. Vis. Sci. 2014;55(13):257.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: Pregnancy is a known predisposing factor for central serous chorioretinopathy (CSC). Choroidal thickness (CT) increases in patients with CSC. This study was designed to evaluate changes in CT during pregnancy.

Methods: This was an observational study. Fourteen healthy pregnant women and seven patients with pre-eclampsia were included. Twenty-one normal subjects were also recruited. CT was measured using enhanced-depth imaging optical coherence tomography (EDI-OCT).

Results: The mean CT values of normal subjects, healthy pregnant women, and patients with preeclampsia were 264±21.03, 274.23±18.97, and 389.79±25.13 µm, respectively (normal subjects vs. healthy gravidas: P>0.05; normal subjects vs. preeclampsia: P<0.001; healthy gravidas vs. pre-eclampsia: P<0.001). CT decreased from 381.05 ± 22.96 µm to 335.17±9.97µm 1 week after delivery in patients with pre-eclampsia.

Conclusions: Pregnancy itself did not increase CT, whereas pre-eclampsia did appear to result in increased CT. This suggests that additional unknown factors induce hyperpermeability in pregnant women. An ophthalmic examination, including OCT, is recommended for pregnant women.

Keywords: 452 choroid • 552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)  
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