April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Bevacizumab injections in patients with a choroidal neovascular membrane secondary to choroidal osteoma
Author Affiliations & Notes
  • Maria Pefkianaki
    Moorfields Eye Hospital, London, United Kingdom
  • Vasilios Papastefanou
    Moorfields Eye Hospital, London, United Kingdom
    St Bartholomew`s Hospital, London, United Kingdom
  • Richard Andrews
    Moorfields Eye Hospital, London, United Kingdom
  • Victoria Cohen
    Moorfields Eye Hospital, London, United Kingdom
    St Bartholomew`s Hospital, London, United Kingdom
  • Mandeep S Sagoo
    Moorfields Eye Hospital, London, United Kingdom
    St Bartholomew`s Hospital, London, United Kingdom
  • Footnotes
    Commercial Relationships Maria Pefkianaki, None; Vasilios Papastefanou, None; Richard Andrews, None; Victoria Cohen, None; Mandeep Sagoo, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 3097. doi:
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      Maria Pefkianaki, Vasilios Papastefanou, Richard Andrews, Victoria Cohen, Mandeep S Sagoo; Bevacizumab injections in patients with a choroidal neovascular membrane secondary to choroidal osteoma. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3097.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To present the outcomes of a series of patients with choroidal neovascular membrane (CNV) secondary to a choroidal osteoma.

Methods: In this retrospective series patients underwent complete clinical and imaging assessment (fundus photo, fluorescein angiography and optical coherence tomography) and were managed with intravitreal anti-VEGF injections. Visual acuity and central retinal thickness were recorded pre treatment and at the end of follow up period.

Results: Six patients were included in this study. Of this, 4/6 had predominantly classic or classic and 2/6 patients had minimally classic or occult CNV. Treatment with intravitreal anti-VEGF was applied in all cases (1-3 injections of bevacizumab). Median follow up was 6 months (6-10 months). Visual acuity improved in all patients by 2-6 Snellen lines. CNV completely regressed in 4 cases and partially regressed in 2 cases. Central retinal thickness change ranged from -222 μm to +60 μm.

Conclusions: Intravitreal bevacizumab is an effective treatment modality in the management of vision threatening choroidal neovascular membrane secondary to choroidal osteoma

Keywords: 624 oncology  
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