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Panagiotis Salvanos, Tor Paaske Utheim, Morten Carstens Moe, Ragnheidur Bragadottir, Nils Eide; Autofluorescence Pattern of Optic Disc Melanocytoma. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3100.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the autofluorescence changes caused by optic disc melanocytoma (ODM).
Three eyes from 3 patients with ODM were included. Ultra-widefield autofluorescent images (UW-FAF) were obtained with the 532nm laser (Optomap P200Tx).
Mean patient age was 44 years. Mean follow-up time from the time of first observation was 16.5 years. Best-corrected visual acuity was 20/25. Clinical examination revealed a dome-shaped, darkly pigmented tumor on or adjacent to the optic disc in all patients, with a mean tumor basal dimension 1.3 mm and mean tumor thickness by ultrasonography 1 mm. UW-FAF revealed a totally hypofluorescent mass with sharply demarcated, feathery edges on or adjacent to the optic disc. No hyperfluorescent changes due to orange pigment or subretinal fluid in the tumor area or the periphery were seen. There was no major discrepancy in the size of the tumor between autofluorescent images and ophthalmoscopy.
UW-FAF imaging is a novel, noninvasive adjuvant tool in the differential diagnosis of pigmented fundus lesions and might offer more insight in the pathophysiology of optic disc melanocytoma.
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