April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Clinical Outcomes of Phototherapeutic Keratectomy after treatment of Epithelial Basement Membrane Dystrophy and Salzmann's nodular corneal dystrophy
Author Affiliations & Notes
  • Carson Lam
    Ophthalmology, Stanford, Mountain View, CA
  • Edward E Manche
    Ophthalmology, Stanford, Mountain View, CA
  • Footnotes
    Commercial Relationships Carson Lam, None; Edward Manche, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 3121. doi:
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      Carson Lam, Edward E Manche; Clinical Outcomes of Phototherapeutic Keratectomy after treatment of Epithelial Basement Membrane Dystrophy and Salzmann's nodular corneal dystrophy. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3121.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To evaluate the outcomes, recurrances and clinical changes in the treatment of epithelial basement membrane dystrophy (EBMD) and Salzmann's nodular corneal dystrophy (SNCD) patients with phototherapeutic keratectomy (PTK)

Methods: A cross-sectional, clinic-based study was performed.125 eyes of 101 patients diagnosed with EBMD or SNCD who underwent PTK between 2000 and 2012 at our institution. Preoperative and Postoperative records were reviewed. Symptoms, clinical findings, uncorrected and corrected visual acuity were collected.

Results: Mean follow-up time was 13 months. Among patients treated for EBMD 71% had improved visual acuity, 9% had the same acuity, 20% had poorer acuity and 89% had resolution of clinical findings and symptoms at the time of follow up. Among the SNCD group 42% had improved visual acuity, 24% had the same acuity, 14% had poorer acuity and 83% had resolution of clinical findings and symptoms at the time of follow up. 17% in the SNCD and 31% in the EBMD group required repeat PTK

Conclusions: PTK is an effective for both EBMD and Salzmann's nodular corneal dystrophy. The relationship between the postoperative clinical improvement, corneal morphologic features and PTK method requires further investigation.

Keywords: 479 cornea: clinical science • 482 cornea: epithelium • 462 clinical (human) or epidemiologic studies: outcomes/complications  
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