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Jack Parker, Korine van Dijk, Gerrit Melles, Netherlands Institute for Innovative Ocular Surgery; Bowman layer implantation: an alternative to penetrating or deep anterior lamellar keratoplasty in eyes with advanced keratoconus. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3130.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the efficacy of Bowman layer (BL) implantation in reducing and stabilizing corneal ectasia in patients with advanced keratoconus (AKC) and contact lens intolerance, not eligible for either UV-crosslinking (UVCXL) or intracorneal ring segments (ICRS).
Ten eyes of 9 patients with AKC and contact lens intolerance, not candidates for either UVCXL or ICRS, underwent mid-stromal implantation of an isolated Bowman membrane and were followed for a mean duration of 16 months.
All surgeries were uneventful and no complications related to BL implantation were observed. Maximum corneal power decreased, on average, from 74.5D (±7.1D) to 68.3D (±5.6D) (P=0.00). No changes in best corrected visual acuity (P=0.77) or pachymetry (P=0.11) were discovered, and contact lens tolerance was restored in all eyes.
For eyes with AKC, not candidates for either UVCXL or ICRS, BL implantation may be a safe and effective method of treating ectasia, enabling continued contact lens wear and postponing penetrating or deep anterior lamellar keratoplasty.
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