Abstract
Purpose:
To determine the survival corneal graft rate in children after Penetrating Keratoplasty at the Fundacion Hospital Nuestra Señora de la Luz in Mexico City.
Methods:
This is a descriptive study, where we reviewed the files of children undergoing Penetrating Keratoplasty at the Cornea department in the Fundacion Hospital Nuestra Señora de la Luz in Mexico City. The following variables were included: Fron the Donor tissue: donor age, time between death and procuration, days between procuration and surgery and cell density. The host variables were diagnosis, age, sex, graft survival rate and graft failure at least with one year follow up. A survival analysis (Kaplan-Meller) and a parametric analysis was done.
Results:
We included forty five children in the study with a range age of 1 year-18 years. The principal preoperative diagnosis was keratoconus, followed by congenital anomalies and infectious diseases. More than 50% of the patients had a corneal graft rejection and 55% resulted in a corneal graft failure. Parametric analysis and survival analysis was made.
Conclusions:
Children under 18 years old have a minor corneal survival rate at one year follow up. Preoperative diagnosis, host age and donor tissue with a high cell density have a close relationship with graft success.
Keywords: 479 cornea: clinical science •
669 quality of life •
462 clinical (human) or epidemiologic studies: outcomes/complications