April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Chronological Characteristic Analysis of Corneal Transplantations at a Single Tertiary Referral Hospital
Author Affiliations & Notes
  • Yongjae Cha
    Department of Ophthalmology, Seoul National University, Seoul, Republic of Korea
    Laboratory of Ocular Regenerative Medicine and Immunology, Artificial Eye Center, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea
  • Hyuk Jin Choi
    Laboratory of Ocular Regenerative Medicine and Immunology, Artificial Eye Center, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea
    Department of Ophthalmology, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Republic of Korea
  • Joon-Young Hyon
    Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
  • Young Keun Han
    Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul, Republic of Korea
  • Joo Youn Oh
    Department of Ophthalmology, Seoul National University, Seoul, Republic of Korea
    Laboratory of Ocular Regenerative Medicine and Immunology, Artificial Eye Center, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea
  • Won Ryang Wee
    Department of Ophthalmology, Seoul National University, Seoul, Republic of Korea
    Laboratory of Ocular Regenerative Medicine and Immunology, Artificial Eye Center, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea
  • Mee Kum Kim
    Department of Ophthalmology, Seoul National University, Seoul, Republic of Korea
    Laboratory of Ocular Regenerative Medicine and Immunology, Artificial Eye Center, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea
  • Footnotes
    Commercial Relationships Yongjae Cha, None; Hyuk Jin Choi, None; Joon-Young Hyon, None; Young Keun Han, None; Joo Youn Oh, None; Won Ryang Wee, None; Mee Kum Kim, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 3135. doi:
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      Yongjae Cha, Hyuk Jin Choi, Joon-Young Hyon, Young Keun Han, Joo Youn Oh, Won Ryang Wee, Mee Kum Kim; Chronological Characteristic Analysis of Corneal Transplantations at a Single Tertiary Referral Hospital. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3135.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract 
 
Purpose
 

To investigate the chronological changes of corneal transplantation in purposes, underlying causes, accompanying risk factors, surgical techniques, mean postoperative best corrected visual acuity and graft survival rate before and after the time-point (2004) of wide use of foreign imported corneas.

 
Methods
 

Consecutive medical records of 375 eyes underwent corneal transplantation between 2000 and 2012 at a single tertiary referral center were retrospectively reviewed and randomly selected. Main indications for corneal transplantations were classified into optical, therapeutic, and tectonic purposes and underlying causes were divided into 11 different corneal disease categories. Known 43 potential demographic, preoperative, intraoperative, and donor risk factors for graft rejection were collected. Surgical methods applied to each case were also reviewed.

 
Results
 

The overall graft survival rate of domestic and imported cornea were 44.2% and 63.8% respectively. In the order of frequency, main purposes were optical (93.9%), tectonic(2.4%), and therapeutic (2.4%) before 2004 compared with optical (90.8%), therapeutic (4.8%) and tectonic (4.4%) after 2004. Main diagnoses were postinfectious scarring (30.5%), regraft (17.1%), corneal opacity due to unknown cause (15.9%) before 2004 and were regraft (29.4%), corneal opacity due to unknown cause (18.4%), postinfectious scarring (15.0%) after 2004. The proportion of corneal neovascularization range wider than 1 quadrant was 48.8% before 2004 and 63.5% after 2004. The proportion of concurrent cataract surgery was 18.3% before 2004 and 25.6% after 2004. Mean postoperative best corrected logMAR visual acuity was 1.11 before 2004 and 0.80 after 2004.

 
Conclusions
 

Wide use of foreign imported cornea diversified indications for corneal transplantations, increased surgeries in patients with higher risks for rejection, and enabled more complicated surgical procedures.

 
Keywords: 741 transplantation  
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