April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Analysis of factors affecting the graft rejection and graft failure in imported donor corneas
Author Affiliations & Notes
  • Soo Jeong Ryu
    Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea
    Ophthalmology, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea
  • Young Geun Han
    Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea
    Ophthalmology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea
  • Joon-Young Hyon
    Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea
    Ophthalmology, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea
  • Footnotes
    Commercial Relationships Soo Jeong Ryu, None; Young Geun Han, None; Joon-Young Hyon, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 3137. doi:https://doi.org/
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      Soo Jeong Ryu, Young Geun Han, Joon-Young Hyon; Analysis of factors affecting the graft rejection and graft failure in imported donor corneas. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3137. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To evaluate the affecting factors for graft rejection and graft failure in PKP with imported donor corneas

Methods: This is retrospective study that include 110 eyes which PKP with imported donor cornea . Mean follow up period was 18months. Correlation of the graft failure and graft rejection with the following factors were analyzed : donor age, donor sex, donor cause of death, endothelial cell count at the moment of preservation, death-to-preservation time, preservation to surgery time

Results: 54 eyes graft rejection and 42 eyes graft failure occurred. Mean endothelial cell count of imported donor corneas at the moment of preservation was 2887 ± 432 cells/mm2, death to preservation time 9.1 ± 4.8 hours, preservation to surgery time 130.0 ± 25.0 hours. There was no significant correlations between surgical outcome and donor age, donor cornea endothelial cell count, death-to-preservation time, preservation to surgery time.(p=0.952, p=0.522, p=0.335, p=0.616)

Conclusions: Environmental change and long preservation time of imported donor cornea does not affect surgical outcome

Keywords: 479 cornea: clinical science  
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