April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Tectonic graft using preserved human scleral tissue for urgent treatment of perforated cornea due to infectious keratitis
Author Affiliations & Notes
  • Hyung-Joon Kim
    Department of Ophthalmology, Daegu Catholic Univ Hospital, Daegu, Republic of Korea
  • Sook Hyun Yoon
    Department of Ophthalmology, Daegu Catholic Univ Hospital, Daegu, Republic of Korea
  • Footnotes
    Commercial Relationships Hyung-Joon Kim, None; Sook Hyun Yoon, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 3149. doi:
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      Hyung-Joon Kim, Sook Hyun Yoon; Tectonic graft using preserved human scleral tissue for urgent treatment of perforated cornea due to infectious keratitis. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3149.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To investigate the effect of tectonic graft using preserved human scleral tissue for the urgent treatment of corneal perforations caused by infectious corneal ulcer

Methods: Eyes with intractable infectious keratitis which developed corneal perforation larger than 2mm were surgically treated with a urgent tectonic graft using preserved human scleral tissue. Subsequent penetrating keratoplasty were performed and evaluated more than 12 months.

Results: In our study, 5 eyes had bacterial keratitis, 3 eyes had fungal keratitis, and 2 eyes had herpes simplex keratitis. After the initial graft, anatomical success was achieved in 8 eyes. In two eyes a graft melting was developed secondary to delayed epithelial healing. Visual acuity was improved in 6 eyes that received subsequent penetrating keratoplasty and no rejection was developed during the follow-up period of more than 12 months.

Conclusions: This study showed that tectonic graft using preserved human scleral tissue is useful method for urgent purpose in acutely perforated corneal ulcer. To enhance the anatomical success of the graft, the healing of the overlying epithelium over the sclera is essential.

Keywords: 479 cornea: clinical science • 741 transplantation • 708 sclera  
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