April 2014
Volume 55, Issue 13
ARVO Annual Meeting Abstract  |   April 2014
Morphology and Microstructure by en face OCT of Cystoid Cavities in Full Thickness Macular Holes
Author Affiliations & Notes
  • Bruno Lumbroso
    Centro Oftalmologico Mediterraneo, Rome, Italy
  • Cristina Savastano
    Centro Oftalmologico Mediterraneo, Rome, Italy
    Ophthalmology, Catholic University, Rome, Italy
  • Marco Rispoli
    Centro Oftalmologico Mediterraneo, Rome, Italy
  • Footnotes
    Commercial Relationships Bruno Lumbroso, None; Cristina Savastano, None; Marco Rispoli, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 325. doi:
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      Bruno Lumbroso, Cristina Savastano, Marco Rispoli; Morphology and Microstructure by en face OCT of Cystoid Cavities in Full Thickness Macular Holes. Invest. Ophthalmol. Vis. Sci. 2014;55(13):325.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: Purpose: To compare Optical Coherence Tomography (OCT) transverse images at different retina levels in Full Thickness Macular Holes (FTMH) to understand the macular microstructure by en face OCT scans. In this presentation, we describe the different patterns of cystoid cavities of each retinal layers in macular holes, using transverse OCT. The aim of the study is to investigate the details of OCT en face images at different layer levels to understand the correlations between macular microstructure and edema cavities morphology.

Methods: Methods: 24 eyes of 24 patients affected by cystoid cavities secondary to FTMH were evaluated by en face scans at different depths in the retina following exactly inner nuclear layer, outer plexiform layer and Henle layer and outer nuclear layer in eyes. We used transverse scans from Heidelberg Spectralis and from Optovue RTVue to generate tridimensional shape. The scan that better fitted to the interested layer was chosen to observe each layer isolated from the others.

Results: Results: All eyes assessed with enface OCT showed morphological details corresponding to the analyzed layers. At Inner nuclear layer (INL) and Inner Plexiform Layer (IPL) the cavities are small and rounded related to the vertical part of Muller cells and Henle fiber. In the Outer Plexiform Layer (OPL) and Outer Nuclear Layer (ONL), cavities were larger. The shape and dimension of edema cavities in these layers were consistent with horizontal enlarged Muller cells bodies and the cavity separations were slanted.

Conclusions: Conclusions: Enface OCT images provide a new layers analysis possibility in cystoid cavities related to FTMH. Macula microstructure visualization allows a better understanding and interpretation of Muller cells and Henle’s fibers structure in macular disorders.

Keywords: 552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • 586 macular holes • 688 retina  

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