April 2014
Volume 55, Issue 13
ARVO Annual Meeting Abstract  |   April 2014
Multimodal imaging of epimacular membranes
Author Affiliations & Notes
  • Aurelie Brolly
    CHNO des quinze-vingts, Paris, France
  • Hassiba Bouakkaz
    CHNO des quinze-vingts, Paris, France
  • Sarah Ayello-Scheer
    CHNO des quinze-vingts, Paris, France
  • Céline Devisme
    CHNO des quinze-vingts, Paris, France
  • Alexandre Leseigneur
    CHNO des quinze-vingts, Paris, France
  • Jose Alain Sahel
    CHNO des quinze-vingts, Paris, France
  • Michel Paques
    CHNO des quinze-vingts, Paris, France
  • Footnotes
    Commercial Relationships Aurelie Brolly, None; Hassiba Bouakkaz, None; Sarah Ayello-Scheer, None; Céline Devisme, None; Alexandre Leseigneur, None; Jose Sahel, None; Michel Paques, Imagineye (C)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 329. doi:
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      Aurelie Brolly, Hassiba Bouakkaz, Sarah Ayello-Scheer, Céline Devisme, Alexandre Leseigneur, Jose Alain Sahel, Michel Paques; Multimodal imaging of epimacular membranes. Invest. Ophthalmol. Vis. Sci. 2014;55(13):329.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: To document the earliest stages of epiretinal membranes (ERMs) and the effect of the surgery using adaptive optics (AO)

Methods: Prospective study of 23 patients with ERMs at various stages examined by AO flood imaging (ImagineEye, Orsay, France). Thirteen were observed over up to 18 months; while 10 underwent surgery and were followed one year.

Results: AO allowed identifying ERMs at a very early stage (i.e. measuring less than 250µm); they were often plurifocal and located preferentially around vessels. Because ERMs were in all case highly anisotropic, multi-incidence analysis allows a better delimitation. The surface of ERMs presented a combination of diffuse blurring surrounding a myriad of highly reflective, dots 10- 20 µm in diameter. In some cases, a noncontractile progression front surrounded the retractile center. Retinal folds molded retinal vessels. ERMS could be distinguished from the foldings of the inner limiting membrane. After surgery, retinal unfolding was noted, as well as residual ERM and early recurrences.

Conclusions: AO is highly sensitive for the diagnosis of ERMs, and the delimitation of their extent. AO should also help understanding the pathogenesis of the membranes and their progression. AO may be of interest for the follow up of patients at risk for developing vitroretinal proliferation, for instance following retinal detachment surgery.

Keywords: 550 imaging/image analysis: clinical • 585 macula/fovea  

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