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April Harris; 5-line Raster versus MAP(volumetric) images in Optical Coherence Tomography(OCT) imaging for the detection of fluid in exudative Age-Related Macular Degeneration(AMD).. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3409.
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MAP images are more time consuming to review in comparison with 5-line Raster images when evaluating patients with exudative AMD. The purpose is to investigate whether MAP images in OCT imaging confer a significant advantage over 5-line Raster images in detecting either subretinal or intraretinal fluid.
A retrospective analysis of 94 set of images from 94 eyes in 72 consecutive patients receiving anti-VEGF therapy for exudative AMD was performed to determine if intraretinal and/or subretinal fluid present on MAP images was also detected on 5-line Raster images obtained on the same Cirrhus high definition(HD)-OCT(Carl Zeiss Meditec Inc.) machine at the same visit. All 94 patients had either intraretinal or subretinal fluid on MAP imaging.
18 eyes in 16 patients had either intraretinal or subretinal fluid on MAP imaging that was not present on 5-line Raster imaging. This resulted in 19.2% of eyes exhibiting fluid on MAP imaging that was not detected on 5-line Raster imaging. The sensitivity of 5-line Raster imaging to detect fluid in patients with known fluid on MAP OCT imaging was 0.81[95% confidence interval of 0.71-0.88].
Although 5-line Raster OCT imaging is faster and more convenient to review than MAP imaging, there is the possibility of missing a significant number of patients with fluid utilizing the former method. This could result in under treatment of patients with exudative AMD who are treated based on paradigms using OCT imaging.
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