April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Spectral domain optical coherence tomography and fundus autofluorescence of persistent submacular fluid after surgery for retinal detachment
Author Affiliations & Notes
  • Joshua Fernandes
    Ophthalmology, Northwestern University, Chicago, IL
  • Dilraj Singh Grewal
    Ophthalmology, Northwestern University, Chicago, IL
  • Alice T Lyon
    Ophthalmology, Northwestern University, Chicago, IL
  • Manjot Gill
    Ophthalmology, Northwestern University, Chicago, IL
  • Footnotes
    Commercial Relationships Joshua Fernandes, None; Dilraj Grewal, None; Alice Lyon, None; Manjot Gill, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 3421. doi:
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      Joshua Fernandes, Dilraj Singh Grewal, Alice T Lyon, Manjot Gill; Spectral domain optical coherence tomography and fundus autofluorescence of persistent submacular fluid after surgery for retinal detachment. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3421.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To evaluate the spectral domain optical coherence tomography (SD-OCT) and fundus autofluorescence (FAF) findings of persistent submacular fluid (SMF) after surgery for macula-involving retinal detachment.

Methods: Retrospective review of 20 eyes of 20 patients with uncomplicated, macula-involving rhegmatogenous retinal detachments who underwent successful retinal detachment repair with pars plana vitrectomy or combined pars plana vitrectomy and scleral buckle. All patients underwent clinical examination, SD-OCT, and FAF of the macula preoperatively and post-operatively for up to two years. Patients who were found to have persistent SMF on SD-OCT after surgery were identified and their imaging characteristics, duration of fluid and associations with visual outcome were further analyzed.

Results: Six out of twenty eyes were identified with persistent SMF on SD-OCT following surgery. Other SD-OCT features identified post-operatively were photoreceptor outer segment irregularity, inner segment/ outer segment disruption, external limiting membrane discontinuity and outer nuclear layer changes. The SMF gradually resolved in all cases between 6 months to 2 years and was associated with a delayed improvement in visual acuity and slow improvement in the other associated SD-OCT abnormalities. Four patients showed a patchy hypoautofluorescence pattern, which correlated to pockets of SMF and ultrastructural abnormalities on SD-OCT early in the post-operative course. These areas ultimately became hyperautofluorescent in the late follow-up period. Two patients showed a curvilinear hyperautofluorescence pattern early in the post-operative course.

Conclusions: Persistent SMF after successful retinal detachment surgery may persist for months to years and can cause delayed visual recovery. FAF changes may correspond with areas of persistent SMF and ultrastructural changes in the SD-OCT, which suggests a potential role of RPE dysfunction in this disease process.

Keywords: 697 retinal detachment • 688 retina • 762 vitreoretinal surgery  
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