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Sharad Malavade, Brian Madow; Prevalence of Subretinal Drusenoid Deposits in non- Age related Macular Degeneration retinal disease.. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3431.
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To determine the prevalence of sub-retinal drusenoid deposits (SDD) in non-Age-related Macular Degeneration (non-AMD) patients.
Images from Heidelberg Spectralis Spectral Domain Optical Coherence Tomography (SDOCT) were selected from a random sample of 52 patients (87eyes). Eyes with no SDD (n=36) or whose medical records could not be accessed (n=12) were excluded from the study. OCT reviewers were blinded to diagnosis at the time of review. Subsequently, the clinical diagnosis of the eyes was determined from the charts.
Amongst the eyes with SDD, 66 % eyes had AMD (n=26). Of these, 57.64% (n=15) had dry AMD and remaining had wet AMD. 12.8% of the SDD were seen in eyes with choroidal tumors like nevi and melanomas (n=4). 15.36% eyes with SDD had other diagnoses like epiretinal membrane (n=3), diabetic retinopathy (n=2) and retinal angioma in von Hippel Lindau syndrome (n=1), regressed B cell lymphoma (n=1) and a normal eye.
SDD are commonest in AMD patients. However, they are also seen in other conditions like choroidal tumors, epiretinal membrane and diabetic retinopathy.
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