Abstract
Purpose:
To determine the prevalence of sub-retinal drusenoid deposits (SDD) in non-Age-related Macular Degeneration (non-AMD) patients.
Methods:
Images from Heidelberg Spectralis Spectral Domain Optical Coherence Tomography (SDOCT) were selected from a random sample of 52 patients (87eyes). Eyes with no SDD (n=36) or whose medical records could not be accessed (n=12) were excluded from the study. OCT reviewers were blinded to diagnosis at the time of review. Subsequently, the clinical diagnosis of the eyes was determined from the charts.
Results:
Amongst the eyes with SDD, 66 % eyes had AMD (n=26). Of these, 57.64% (n=15) had dry AMD and remaining had wet AMD. 12.8% of the SDD were seen in eyes with choroidal tumors like nevi and melanomas (n=4). 15.36% eyes with SDD had other diagnoses like epiretinal membrane (n=3), diabetic retinopathy (n=2) and retinal angioma in von Hippel Lindau syndrome (n=1), regressed B cell lymphoma (n=1) and a normal eye.
Conclusions:
SDD are commonest in AMD patients. However, they are also seen in other conditions like choroidal tumors, epiretinal membrane and diabetic retinopathy.
Keywords: 504 drusen •
552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) •
412 age-related macular degeneration