April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
DIFFUSERS INDUCED OCULAR LIGHT SCATTERING MEASURED BY A PSYCHOPHYSICAL AND AN OPTICAL METHOD
Author Affiliations & Notes
  • Marrie Van der Mooren
    Applied Research, AMO Groningen BV, Groningen, Netherlands
  • Harilaos S Ginis
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
  • Robert Rosén
    Applied Research, AMO Groningen BV, Groningen, Netherlands
  • Antonio Benito
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
  • Luuk Franssen
    Applied Research, AMO Groningen BV, Groningen, Netherlands
  • Alexandros Pennos
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
  • Dimitrios Christaras
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
  • Patricia A Piers
    Applied Research, AMO Groningen BV, Groningen, Netherlands
  • Pablo Artal
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
  • Footnotes
    Commercial Relationships Marrie Van der Mooren, Abbott Medical Optics Inc (E); Harilaos Ginis, Abbott Medical Optics Inc. (F), WO 2012/146813 (P); Robert Rosén, Abbott medical Optics Inc. (E); Antonio Benito, Abbott Medical Optics Inc. (F); Luuk Franssen, Abbott Medical Optics Inc. (E); Alexandros Pennos, Abbott Medical Optics Inc. (F); Dimitrios Christaras, Abbott Medical Optics Inc. (F); Patricia Piers, Abbott Medical Optics Inc. (E); Pablo Artal, Abbott Medical Optics Inc. (C), Abbott Medical Optics Inc. (F), WO 2012/146813 (P)
  • Footnotes
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Investigative Ophthalmology & Visual Science April 2014, Vol.55, 3781. doi:
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      Marrie Van der Mooren, Harilaos S Ginis, Robert Rosén, Antonio Benito, Luuk Franssen, Alexandros Pennos, Dimitrios Christaras, Patricia A Piers, Pablo Artal; DIFFUSERS INDUCED OCULAR LIGHT SCATTERING MEASURED BY A PSYCHOPHYSICAL AND AN OPTICAL METHOD. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3781.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

Inhomogeneity in the aging crystalline lens and voids in intraocular lenses (IOLs) cause light to scatter and potentially may deteriorate quality of vision. We evaluated photographic diffusers filters mimicking micro vacuoles in IOLs. The impact of these filters on straylight level was measured using two methods.

 
Methods
 

Four photographic diffusers introducing different amount of light scattering (Pro-Mist Black ¼, ½, 1, and 2. The Tiffen Company, NY, USA) were first characterized in vitro. Subsequently, the increase of straylight that the filters induce when introduced in front of subjects’ eyes was measured by a psychophysical and an optical method. A straylight parameter was measured in six subjects using the compensation comparison method (C-Quant, OCULUS, Germany) with the glare source positioned at 7 degrees and at 2.5 degrees. Three of the same subjects were measured with an optical integrator method (Ginis et al., JOV, 2012) that reconstruct the eye’s point spread function with an angular extend of up to 8.1 degrees. An optical straylight parameter over the angular range from 3 to 7 degrees was determined for each filter.

 
Results
 

The induced straylight parameter of the filters measured by the C-Quant ranged from 0.8 to 1.4 for the glare source at 2.5° and from 0.3 to 1.0 at 7°. The induced average straylight level measured by the optical method increased as the filters becomes more diffuse and ranged from 0.2 to 0.7. These results indicate that filters ¼ and ½ represent values for the condition of micro-vacuoles present in IOLs and filters 1 and 2 produce values resembling cataract. An undesired side effect was the different absorption levels of the filters that may impact retinal illuminance.

 
Conclusions
 

Both methods showed on average an increase in straylight induced for each filter. These results indicate that the diffuser filters are helpful in quantifying the straylight effect for ocular conditions ranging from microvacuoles in IOLs to cataract.

 
Keywords: 630 optical properties • 641 perception • 567 intraocular lens  
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