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Keiichiro Minami, Masato Honbou, Yosai Mori, Kazunori Miyata; Evaluation of Surface Light Scattering and Posterior Capsular Opacification Using Rotating Scheimpflug Imaging System. Invest. Ophthalmol. Vis. Sci. 2014;55(13):3782.
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© ARVO (1962-2015); The Authors (2016-present)
Densitometry of Scheimpflug photography had been used for quantitatively evaluating surface light scattering and posterior capsular opacification (PCO) in implanted intraocular lens (IOL). Although advanced instruments based on Scheimpflug imaging have been developed, they were rarely used for evaluating implanted IOLs. This prospective study was to examine the use of rotating Scheimpflug imaging system in the densitometry measurement of implanted IOL.
The study comprised with 177 eyes of 110 patients who were implanted hydrophobic acrylic IOLs 6 months to 16 years (mean: 4.0±3.7 years) ago. There were 155 eyes receiving IOLs that increased surface light scattering over time. Scheimpflug images of IOL were obtained using Pentacam (Oculus) and EAS-1000 (Nidek). Pentacam was a rotating Scheimpflug imaging system that provided full-angle images (rotation mode) and a single image with averaging of 15 images (single mode), while EAS-1000 captured a image under a flash lamp illumination. From the transverse image, area densitometries in the central 3 mm diameter were measured on anterior and posterior IOL surfaces. Correlations with the EAS-1000 results were evaluated by linear regression analysis.
Mean densitometries on the anterior and posterior surfaces were 7.1 and 6.2 in rotation mode and 13.5 and 11.6 in single mode, respectively. Intensity in single mode was 1.8 times higher than rotation mode. Significant correlations with the EAS-1000 results were found in densitometry on the anterior surface (P<0.001, R2=0.95 in rotation mode, 0.91 in single mode) when EAS-1000 densitometry was less than 150 CCT. On the posterior surface, there were also significant correlations (P<0.001) as well: R2 in rotation and single modes were 0.76 and 0.71. The linear correlations on both IOL surfaces were deviated when EAS-1000 densitometry exceeded 150 CCT.
Densitometry with the rotating Scheimpflug imaging system was effective for evaluating surface light scattering and PCO, and well comparable with EAS-1000 measurement. The previous studies using EAS-1000 showed that densitometry beyond 150 CCT was rare and found in cases over 15 years postoperatively. Therefore, the assessment using a rotating Scheimpflug imaging could replace the previously used EAS-1000 examination.
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