Abstract
Purpose:
To describe the diverse patterns observed with the use of Ultra-wide-field images in patients with Birdshot chorioretinopathy (BSCR)
Methods:
A chart review of patients with BSCR seen at Clinic Hospital of Barcelona, who had ultra-wide-field images including retinography, autofluorescence fundus photography and angiography. The data obtained included age, gender, presence of the HLA-A29 haplotype, and current treatment
Results:
Fourty-two eyes of 21 patients with HLA-A29 associated BSCR were included. Of the 42 eyes, 10 eyes (23.8%) showed exclusively posterior choroidal lesions (<45%) and 32 eyes (76%) had both posterior and peripherical choroidal lesions. Sixteen eyes (38%) had retinal pigment epithelium (RPE) atrophy evidenced by hypoautofluorescent regions and 18 eyes had posterior and peripherical hypoautofluorescent lesions. Six (14%) patients showed a mixed pattern of posterior hypo and hyperautofluorescence. Angiography mainly showed vascular leakage from retinal vessels and also cystoid macular edema and disc edema.
Conclusions:
Ultra-Wide-field autofluorescence imaging could appear to be a useful examination in patients with BSCR specially to better determine location of choroidal lesions and inflammation activity by means of autofluorescence and angiography. The BSCR has been classically considered a posterior uveitis with choroidal lesions mainly limited to the posterior pole, our pilot study highlights the presence of peripheral lesions
Keywords: 550 imaging/image analysis: clinical •
745 uvea •
451 chorioretinitis