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Donny W Suh, Sarah H Suh; Anisocoria and Pupillary Size in Pediatric Population and their Correlation with Age. Invest. Ophthalmol. Vis. Sci. 2014;55(13):4115.
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© ARVO (1962-2015); The Authors (2016-present)
To study the pupillary size, frequency and magnitude of anisocoria, and their correlation to age in pediatric patients in a pediatric ophthalmology practice using the plusoptiX A08 photoscreener.
The medical records of consecutive patients, neonates to 9 years of age, were collected and analyzed. All patients had complete ophthalmological examinations that included photoscreening with the plusoptiX A08. Data included age, pupil sizes, and anisocoria.
Of the 799 children, 404 had an anisocoria of 0 to 0.5mm (50.6%), 93 had an anisocoria of 0.6mm to 1.2mm (11.6%), and 27 had an anisocoria of >1.3mm (3.6%). 744 of the children (93.1%) had an anisocoria of 0mm to 1.0mm. There was no correlation between increasing age and severity of anisocoria. The average anisocoria within each age group ranged between 0.46 to 0.60mm with no respect to the age. However, rise in age showed a link with the larger pupillary size (P< 0.005). The average pupillary size of children 0 < 1 year old was 4.76 mm; 1<2 was 4.72 mm; 2<3 was 5.15mm; 3<4 was 5.20mm; 4<5 was 5.49mm; 5<6 was 5.70mm; 6<7 was 5.67; 7<8 was 5.71mm; 8<9 was 5.98mm; and 9 years of age was 6.04mm. The average anisocoria found was 0.51 mm and the mode was 0.4mm (15.7%).
In the study of 799 children, the pupillary size increased with age. The anisocoria remained stable throughout the ages. About half of the pediatric population had an anisocoria up to 0.5 mm.
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