April 2014
Volume 55, Issue 13
ARVO Annual Meeting Abstract  |   April 2014
SF-36 as a quantitative assessment of the quality of life in patients with keratoconus and its relationship to severity of the disease
Author Affiliations & Notes
  • Virgilio Galvis
    Ophthalmology, Centro Oftalmologico Virgilio Galvis, Floridablanca, Colombia
  • Arantxa Acera
    Bioftalmik SL, Derio, Spain
  • Alejandro Tello
    Ophthalmology, Centro Oftalmologico Virgilio Galvis, Floridablanca, Colombia
  • Jesus Merayo-Lloves
    Instituto Oftalmologico Fernandez Vega and University of Oviedo, Oviedo, Spain
  • Tatiana Maria Suarez-Cortes
    Bioftalmik SL, Derio, Spain
  • Footnotes
    Commercial Relationships Virgilio Galvis, None; Arantxa Acera, None; Alejandro Tello, None; Jesus Merayo-Lloves, None; Tatiana Suarez-Cortes, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 4209. doi:
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      Virgilio Galvis, Arantxa Acera, Alejandro Tello, Jesus Merayo-Lloves, Tatiana Maria Suarez-Cortes, Keratoconus CeyeC group; SF-36 as a quantitative assessment of the quality of life in patients with keratoconus and its relationship to severity of the disease. Invest. Ophthalmol. Vis. Sci. 2014;55(13):4209.

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      © ARVO (1962-2015); The Authors (2016-present)

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Keratoconus (KC) is a corneal disease associated with a cone-shaped protrusion and progressive corneal thinning. Correct the optical error induced by an irregular corneal surface is of paramount importance with respect to quality of life and ability to work. Our purpose was to determine if the Impact of SF36-Item Health Survey is a valid questionnaire to measure the vision-related quality of life in bilateral keratoconus patients and to relate it to the severity of the disease.


115 keratoconus patients and 32 healthy subjects (control group) were included in the study. The stage of keratoconus was graded as mild when the steepest keratometric reading (K2) was < 45 diopters (D), moderate if K2 was between 45 and 52 D and severe with K2 >52 D. We considered K2 as the quantitative clinical variable to assess the severity of keratoconus. The parameters studied included patients demographics, clinical features, topography and visual acuity and SF-36 questionnaire.


Both groups were demographically similar and comparable. Mean age was 33.14 ± 7.54 years (40% women and 60 % men) in KC group and 34.19 ± 7.98 years (42% women and 58% men) in control group. The general health status of patients with keratoconus was good (76.71 ± 5.13). However, SF-36 scores showed that patients with severe degree of keratoconus had lowest scores regarding the social and emotional status component (83.66 ± 6.80) as well as the job component (80.04 ± 9.5) (p=0.002).


The SF-36 questionnaire seems to be a useful tool for measuring health-related quality of life in KC patients given its ability to measure health in physical, psychological and social health scales.

Keywords: 574 keratoconus • 669 quality of life  

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