April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Comparison of Anterior Chamber Angle Width Determinants in Different Ethnic Groups
Author Affiliations & Notes
  • Roland Y Lee
    Ophthalmology, University of California, San Francisco, San Francisco, CA
  • Diego Tebaldi de Queiroz Barbosa
    Ophthalmology, University of California, San Francisco, San Francisco, CA
  • Brian Chon
    Ophthalmology, Duke University, Durham, NC
  • Mingguang He
    Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
  • Shan C Lin
    Ophthalmology, University of California, San Francisco, San Francisco, CA
  • Footnotes
    Commercial Relationships Roland Lee, None; Diego Barbosa, None; Brian Chon, None; Mingguang He, None; Shan Lin, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 4296. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Roland Y Lee, Diego Tebaldi de Queiroz Barbosa, Brian Chon, Mingguang He, Shan C Lin; Comparison of Anterior Chamber Angle Width Determinants in Different Ethnic Groups. Invest. Ophthalmol. Vis. Sci. 2014;55(13):4296.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: To evaluate determinants of anterior chamber angle width in Caucasian, African, Hispanic, and Chinese subjects.

Methods: Anterior segment optical coherence tomography images captured before and after LPI were analyzed to determine trabecular-iris space area (TISA750); angle opening distance (AOD750); anterior chamber area (ACA); anterior chamber volume (ACV); anterior chamber width (ACW); lens vault (LV); iris thickness (IT750); and iris area (IArea). Comparisons of ACA, ACV, ACW, LV, IT750, and IArea were made between ethnic groups for subjects with only narrow angles, only open angles, and both narrow and open angles. Multivariate linear regression models were used to investigate the association of TISA750 and AOD750 with ACA, ACV, ACW, LV, IT750 and IArea.

Results: Data from 157 Caucasian, 73 African, 62 Hispanic, and 124 Chinese subjects were analyzed. Ethnic differences among narrow angle subjects were observed in ACA, ACV, ACW, LV, and IT750, while ethnic differences among open angle subjects were observed in ACV, ACW, LV, IT750, and IArea (all P < 0.05). Merging both narrow angle and open angle subjects together showed ethnic differences in ACA, ACV, ACW, LV, IT750, and IArea (all P < 0.05). In all four ethnic groups, ACA, ACV, ACW, LV, IT750 and IArea were significant predictors of variance in both TISA750 and AOD750 (all P < 0.05). ACA, ACV, and ACW were the strongest determinants of both TISA750 and AOD750 across all ethnicities.

Conclusions: Despite ethnic differences in ACA, ACV, ACW, LV, IT750 and IArea, these six anterior segment biometric parameters feature as significant determinants of anterior chamber angle width in all four ethnic groups.

Keywords: 420 anterior chamber • 550 imaging/image analysis: clinical  
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×