Abstract
Purpose:
To study the efficacy of intravitreal bevacizumab (IVB) for macular edema with Central retinal vein occlusion (CRVO).
Methods:
Subjects were 15 eyes of 15 consecutive patients (mean age, 64.1) in our hospital with macular edema from CRVO (15cases) treated by bevacizumab from Jan. 1st 2009 to Dec. 31st 2009. The patients were followed at least 3 months. Results were examined retrospectively by BCVA and macular thickness measured with optical coherence tomography (OCT).
Results:
Mean best-corrected visual acuity (BCVA) rose from 0.34 to 0.41 on 15 patients with CRVO who were treated by bevacizumab for macular edema. Macular thickness improved from 552μm to 343μm on CRVO patients. Patients who were treated by IVB within 30days after onset had better BCVA of 0.43 while those who were treated after 30 days had BCVA of 0.37.
Conclusions:
Although these are retrospective study results, intravitreal bevacizumab was effective for maintaining good vision and decreased macular edema on Central retinal vein occlusion. It was more effective to treat by IVB within 30 days.
Keywords: 585 macula/fovea •
505 edema •
748 vascular endothelial growth factor