April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
En-face Imaging of Cysts and Exudates Using Mixtures of Segmentations
Author Affiliations & Notes
  • Paul F Stetson
    Research and Development, Carl Zeiss Meditec, Dublin, CA
  • Philip J Rosenfeld
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
  • Giovanni Gregori
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
  • Zohar Yehoshua
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 4800. doi:
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    • Get Citation

      Paul F Stetson, Philip J Rosenfeld, Giovanni Gregori, Zohar Yehoshua; En-face Imaging of Cysts and Exudates Using Mixtures of Segmentations. Invest. Ophthalmol. Vis. Sci. 2014;55(13):4800.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: The purpose of this study is to demonstrate visualization of abnormalities in the middle layers of the retina using en-face imaging along a contour defined using both ILM and RPE segmentations, and to show whether this method is superior to using ILM or RPE segmentations alone.

Methods: Data from patients with cystoid macular edema and exudates were gathered from a prototype swept-source OCT system. These image volumes were processed offline with prototype ILM and RPE segmentation algorithms based on those used in the Cirrus™ HD-OCT system. En-face images were then constructed using those segmentations and also using surfaces that were fractions of the distance between the ILM and RPE.

Results: The en-face images that followed the contours of the ILM or RPE alone often showed bands from multiple layers of the retina that obscured the visualization of mid-retinal pathology. En-face images that followed a contour that was a fraction of the distance between the ILM and RPE showed fewer such bands and therefore showed mid-retinal pathology more clearly.

Conclusions: Neither the ILM nor the RPE follow the layers of the retina well in the mid-retinal regions where cysts and exudates are often found. Combining the two contours can reliably construct a surface that approximately follows the contours of the retina, even in highly disrupted regions where mid-retinal layers may be difficult to segment. This technique therefore gives a clear en-face image of the pathology affecting that level of the retina, and this image is often superior to that obtained by en-face imaging using either the ILM or RPE alone.

Keywords: 550 imaging/image analysis: clinical • 551 imaging/image analysis: non-clinical • 552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)  
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