Abstract
Purpose:
To prospectively evaluate changes in speed of pupil constriction (SPC) and anterior segment parameters after phacoemulsification (Phaco) in patients with and without closed angles using anterior segment optical coherence tomography (ASOCT).
Methods:
This was a pilot study of prospective study of patients who underwent standardized Phaco surgery and completed 6 months follow-up (1 week, 1 month and 6 month). ASOCT videography was taken 1 weeks before and 1-2 weeks after Phaco in this pilot study. Videos of pupil and anterior segment changes in response to illumination were captured in 8 open angle and 7 closed angle eyes with real-time video recording using anterior segment optical coherence tomography and were analyzed frame by frame. Customized software was used to measure SPC which was defined as the rate of pupil diameter change in response to illumination. Pair-wise comparisons between groups were conducted by Student’s t-test.
Results:
Before Phaco, the open angle group showed significantly greater angle width measurements (all with p<0.01) (Table 1) and faster SPC (p=0.02) (Table 2). A significant decrease was observed in SPC after Phaco in both open angle and closed angle eyes (1.32 mm/sec vs 1.09 mm/sec for open angle eyes with p<0.05, 1.02 mm/sec vs 0.89 mm/sec for closed angle eyes with p<0.05). After Phaco, no significant difference was found in terms of SPC between open angle and closed angle eyes.
Conclusions:
In patients with and without closed angle, changes in dynamic iridopupillary behavior are observed after Phaco. The speed of pupillary constriction is slower after Phaco.
Keywords: 421 anterior segment •
550 imaging/image analysis: clinical