Abstract
Purpose:
To examine the structural features of retinal angiomatous proliferation and chorioretinal anastomosis in childhood Coats disease.
Methods:
A prospective observational case series of consecutive patients presenting with Coats’ disease over a one year period was performed. Multimodal imaging, including color fundus photography, wide-field fluorescein angiography, and spectral-domain optical coherence tomography (SD-OCT) was used to identify the features of macular retinal angiomatous proliferation and chorioretinal anastomosis observed in patients with macular fibrosis.
Results:
5 of the 21 patients with Coats disease showed distinct characteristics consistent with retinal angiomatous proliferation and chorioretinal anastomosis on color photography, fluorescein angiography, and spectral-domain OCT with doppler enhancement. The lesions appeared as well-demarcated, nodular, retinal pigment epithelial detachments surrounded by exudate, with retinal vessels continuous with the underlying choroidal neovascularization.
Conclusions:
Retinal angiomatous proliferation and chorioretinal anastomoses are common features observed in children with Coats disease. This lesion likely underlies the previous “macular fibrosis” and “subretinal mounds” previously described, and represents a distinct macular variant of Coats disease.
Keywords: 688 retina •
552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) •
452 choroid