April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
A stromal corneal nerves comparison between normal vs fibromyalgia patients by confocal microscopy.
Author Affiliations & Notes
  • Manuel Ramirez
    Cornea, APEC, Mexico City, Mexico
  • Jorge Velazco
    Cornea, APEC, Mexico City, Mexico
  • Laura A Martinez
    Rheumatology, National Institute of Cardiology, Mexico City, Mexico
  • Everardo Hernandez-Quintela
    Cornea, APEC, Mexico City, Mexico
  • Manuel Martinez-Lavin
    Rheumatology, National Institute of Cardiology, Mexico City, Mexico
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 5154. doi:
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    • Get Citation

      Manuel Ramirez, Jorge Velazco, Laura A Martinez, Everardo Hernandez-Quintela, Manuel Martinez-Lavin; A stromal corneal nerves comparison between normal vs fibromyalgia patients by confocal microscopy.. Invest. Ophthalmol. Vis. Sci. 2014;55(13):5154.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To evaluate the stromal corneal nerves differences between normal patients and fibromyalgia patients.

Methods: 16 eyes of 8 normal patients (group A) and 18 eyes of 9 fibromyalgia patients (group B) were examined with the confocal microscope (Confoscan 4, Fortune Technologies, Italy), a central scan of the total corneal thickness was taken. Corneal stromal nerves morphology and thickness were evaluated by using the Navis v. 3.5.0. Software (NIDEK, Multi-Instrument Diagnostic System, Japan). Nerve thickness was obtained from the mean between the widest and the narrowest portion of each stromal nerve.

Results: Corneal stromal nerves were observed as irregular linear hiper-reflective structures with widest and narrowest portions in all cases. Mean corneal stromal nerves thickness in group A was 6.3 ± 1.9, range from 2.9 to 11.4 microns, mean corneal stromal nerves thickness in group B was was 5.8 ± 1.7 range from 2.7 to 11.4 microns . There was not statistical significant difference (P= 0.189) in stromal corneal thickness between group A and group B.

Conclusions: Stromal corneal nerves morphology and thickness was similar in both groups.

Keywords: 479 cornea: clinical science • 484 cornea: stroma and keratocytes • 610 nerve fiber layer  
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