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Manuel Ramirez, Jorge Velazco, Laura A Martinez, Everardo Hernandez-Quintela, Manuel Martinez-Lavin; A stromal corneal nerves comparison between normal vs fibromyalgia patients by confocal microscopy.. Invest. Ophthalmol. Vis. Sci. 2014;55(13):5154.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the stromal corneal nerves differences between normal patients and fibromyalgia patients.
16 eyes of 8 normal patients (group A) and 18 eyes of 9 fibromyalgia patients (group B) were examined with the confocal microscope (Confoscan 4, Fortune Technologies, Italy), a central scan of the total corneal thickness was taken. Corneal stromal nerves morphology and thickness were evaluated by using the Navis v. 3.5.0. Software (NIDEK, Multi-Instrument Diagnostic System, Japan). Nerve thickness was obtained from the mean between the widest and the narrowest portion of each stromal nerve.
Corneal stromal nerves were observed as irregular linear hiper-reflective structures with widest and narrowest portions in all cases. Mean corneal stromal nerves thickness in group A was 6.3 ± 1.9, range from 2.9 to 11.4 microns, mean corneal stromal nerves thickness in group B was was 5.8 ± 1.7 range from 2.7 to 11.4 microns . There was not statistical significant difference (P= 0.189) in stromal corneal thickness between group A and group B.
Stromal corneal nerves morphology and thickness was similar in both groups.
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