Abstract
Purpose:
The sleep apnea syndrome (SAS ) has recently been identified as an independent cardiovascular risk factor, involved in numerous deseases. The aim of our study is to evaluate the prevalence of SAS in patients with retinal vein occlusion (RVO) and to determine the predictive value of a new medical device in the screening of SAS.
Methods:
Prospective study including 30 patients. Each patient had a simplified screening questionary, and an ambulatory respiratory nocturnal events measurement using the device RU- sleeping © (Philips Respironics, Inc.). Ventilatory polysomnography (VPS) is associated in all cases (reference method). The relation between severity of SAS and severity of ischemia in RVO is analysed.
Results:
The mean age of patients is 73.6 years +/- 11, the sex ratio of 1.4 and the distribution between central RVO and branch RVO is as follow : 49% versus 50% . The simplified questionary find signs of SAS in 95% of patients. The prevalence of severe SAS detected by RU- sleeping© is 85.7 % , it is significantly higher than that of the population over 60 years (25 %) (p <0.001). The positive predictive value of Ru -sleeping is 87 % , the negative predictive value of 75 %. The mean macular thickness in SD -OCT is 590 + / - 170μm . A trend appears between the initial macular thickness at RVO diagnosis and severity of SAS.
Conclusions:
The results of this preliminary study show a high prevalence of severe SAS in the RVO population. The benefit of early ventilation on functional and anatomic prognosis in RVO is still unknown .
Keywords: 688 retina •
749 vascular occlusion/vascular occlusive disease •
463 clinical (human) or epidemiologic studies: prevalence/incidence