April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Microbial Keratitis
Daniel Sand; David Chen; Mathew Schur; Ira A Shulman; Hugo Y Hsu
Author Affiliations & Notes
  • Daniel Sand
    Ophthalmology, LAC+USC Medical Center, Los Angeles, CA
  • David Chen
    Keck School of Medicine, University of Southern California, Los Angeles, CA
  • Mathew Schur
    Keck School of Medicine, University of Southern California, Los Angeles, CA
  • Ira A Shulman
    Department of Pathology, Keck School of Medicine at USC, Los Angeles, CA
    Pathology and Laboratory Medicine, LAC+USC Medical Center, Los Angeles, CA
  • Hugo Y Hsu
    Ophthalmology, LAC+USC Medical Center, Los Angeles, CA
    USC Eye Institute, Keck Medical Center of USC, Los Angeles, CA
  • Footnotes
    Commercial Relationships Daniel Sand, None; David Chen, None; Mathew Schur, None; Ira Shulman, None; Hugo Hsu, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 5469. doi:
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      Daniel Sand, David Chen, Mathew Schur, Ira A Shulman, Hugo Y Hsu; Microbial Keratitis. Invest. Ophthalmol. Vis. Sci. 2014;55(13):5469.

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Abstract

Purpose: To evaluate the spectrum and antibiotic susceptibility panel of infectious keratitis at a major county hospital in Southern California.

Methods: IRB approved retrospective review of infectious keratitis cases from 7/1/08 to 12/31/12.

Results: 172 cases were identified. 151 cases (88%) had a positive yield and 92 cases (61%) were monomicrobial. 217 organisms were identified of which 43 were unique. Coagulase-negative Staphylococci was the most commonly identified Gram-positive bacteria and Pseudomonas aeruginosa was the most commonly identified Gram-negative bacteria. 58% of all isolates were resistant to fluoroquinolones and 48% were resistant to gentamicin. 47% of Staphylococcus aureus were ORSA.

Conclusions: Our series revealed that Gram-positive bacteria were the most common pathogen in infectious keratitis cases at our county hospital in Southern California with 42% of all isolates being sensitive to fluoroquinolones.

Keywords: 422 antibiotics/antifungals/antiparasitics • 433 bacterial disease • 479 cornea: clinical science  
© 2014, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2024 Association for Research in Vision and Ophthalmology.
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