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Giorgia Maraone, Giuseppe Mannino, Silvia Calafiore, Cristina Mannino, Martina Maria Delle Fave, Leopoldo Spadea, Enzo M Vingolo; ULTRASOUND BIOMICROSCOPIC DIAGNOSIS OF CILIARY BODY CYSTS AND EVALUATION OF THEIR EFFECT ON ANTERIOR CHAMBER ANGLE. Invest. Ophthalmol. Vis. Sci. 2014;55(13):5860. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the characteristics of size and number of ciliary body cysts and to evaluate changes in the anterior chamber angle
150 consecutive patients with shallow anterior chamber were recruited. All patients had complete clinical examination. All were subjected to ultrasound biomicroscopic (UBM) analysis. Presence, number and diameter of cysts were analyzed. Angle opening distance at 500 µm(AOD500) and trabecular-iris angle (TIA) were measured. All data were examined using T-Student test
Ciliary body cysts were found in 53 patients, prevalence is 35,3%. 25 patients (47,2%) had single cyst, 28 (52,83%) had multiple cysts. Mean size of cysts were 0,96 ± 0,4 mm. 41 patients had open angle (77,36%): 18 of whom had single cyst and 23 had multiple cysts. Mean size of cysts in these patients was 0,81±0,35 mm, average value of AOD500 was 0,11±0,07mm and TIA was 12,48±8,85°. The average of intraocular pressure (IOP) was 17,92 ± 4,14 mmHg. 12 patients had cysts causing corresponding angle closure (22,64%), 7 of whom had a single cyst and 5 had multiple cysts. Mean size of cysts that were causing corresponding angle closure was 1,18±0,4mm. Mean size of cysts that caused closure of the corresponding angle was lower 0,76±0,24 mm in patients with multiple cysts than in patients with single cyst 1,48±0,15 mm, this data was statistically significant (p= 0,017). The average of IOP in this group of patients was19,21± 4,98
Ultrasound biomicroscopy (UBM) is particularly functional in the diagnosis of ciliary body cysts. This technique provides important information regarding location and size of cysts. Patients IOP average was within normal limits. This explains that the closure of a single angular sector does not influence the intraocular pressure. Our results show that the single large cyst causing corresponding angle closure more frequently than the multiple cyst
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