Abstract
Purpose:
To describe the patient-reported wearing experience over time among wearers of hydrogel daily disposable (HydDD) lenses in the TEMPO Registry (NCT#01467557)
Methods:
Registered wearers over age 40 recently fit with 1 DAY ACUVUE MOIST hydrogel daily disposable lenses completed self-administered, branching, electronic questionnaires at 4 times during a year of observation in the Registry. Wearing patterns, replacement schedules, symptoms (by 8-item Contact Lens Dry Eye Questionnaire or CLDEQ-8) and compliance to instructions were queried. Data were analyzed with ANOVA and Signed Rank test as appropriate.
Results:
A cohort of 86 HydDD lens wearers, 24% male, with a mean age of 50.2 ±7.1 years completed surveys. Most (76%) were new to the DD modality, but only 8% were new to CL wear. Their overall opinion of the performance of their CLs increased significantly after refitting with HydDD lenses and remained positive (% excellent/very good 57% at baseline vs. 79%, 69% and 72% at 2 weeks, 4 and 12 months, p<0.05 all time points compared to baseline). Changing to HydDD lenses did not change their average or comfortable wear time (p>0.05), but did significantly improve their CLDEQ-8 symptom score at each time point (baseline 11.2 ±7.3 vs. 7.8 ±5.8 at 2 weeks, p<0.0001; vs. 8.6 ±6.5 at 4 months, p=0.0006; vs. 9.3 ±6.5, p=0.01). Over 90% reported never sleeping in their HydDD lenses, while their compliance to daily replacement reduced between the 2 week and 4 month time points (93% vs. 84%, p=0.007). Wearers self-assessed their compliance as excellent/very good 80% at baseline, but this improved to 98%, 92% and 98% at subsequent visits (p<0.0001).
Conclusions:
Daily disposable lens wearers over age 40 reported significantly higher overall opinions of their lenses, better CLDEQ-8 symptom scores and most are compliant with proper use of their DD lenses. The slippage in daily replacement rates between the 2 week and 4 month time points indicate that reinforcement of that recommendation may be needed. Wearers of reusable CLs over age 40 experienced many benefits from refitting with these DD lenses.
Keywords: 462 clinical (human) or epidemiologic studies: outcomes/complications •
479 cornea: clinical science •
413 aging