April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
Impact of Current and Previous Contact Lens Wear on Meibomian Glands and Tear Film Characteristics.
Author Affiliations & Notes
  • Waleed Alghamdi
    Vision Cooperative Research Centre, Brien Holden Vision Institute, Sydney, NSW, Australia
    School of Optometry & Vision Science, University of New South Wales, Sydney, NSW, Australia
  • Maria Markoulli
    School of Optometry & Vision Science, University of New South Wales, Sydney, NSW, Australia
  • Brien A Holden
    Vision Cooperative Research Centre, Brien Holden Vision Institute, Sydney, NSW, Australia
    School of Optometry & Vision Science, University of New South Wales, Sydney, NSW, Australia
  • Eric B Papas
    Vision Cooperative Research Centre, Brien Holden Vision Institute, Sydney, NSW, Australia
    School of Optometry & Vision Science, University of New South Wales, Sydney, NSW, Australia
  • Footnotes
    Commercial Relationships Waleed Alghamdi, None; Maria Markoulli, None; Brien Holden, None; Eric Papas, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 6065. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Waleed Alghamdi, Maria Markoulli, Brien A Holden, Eric B Papas; Impact of Current and Previous Contact Lens Wear on Meibomian Glands and Tear Film Characteristics.. Invest. Ophthalmol. Vis. Sci. 2014;55(13):6065. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose
 

The aim of this study was to investigate the characteristics of the meibomian glands (MG) and tear film in contact lens wearers (CLW) and previous contact lens wearers (PW) compared to non-wearers (NW).

 
Methods
 

Seventy four participants (mean age ± SD: 25.4 ± 4.4) were recruited as a part of an ongoing cross-sectional study. The following procedures were conducted on 41 CLW, 14 PWs and 19 NWs to investigate: (1) Symptoms of dry eye (Ocular surface disease index); (2) function of MGs and tear film (e.g. MG expressibility, non-invasive break up time (NIBUT), lipid layer thickness, phenol red thread (PRT), tear meniscus cross-sectional area (TMA), tear osmolarity, tear evaporation rate and lid wiper staining); (3) morphology of MGs (MG drop out, Marx line position, and orifices status). A one-way analysis of variance (ANOVA) and Kruskall-Wallis test were used to compare the parametric and non parametric measurements between groups in this study.

 
Results
 

The results of the study are shown in table 1. MG drop-out, evaporation rate, Marx line score, and the number of plugged orifices were significantly higher in CLWs and PWs compared to NWs. MG expressibility score, PRT, NIBUT and TMA were significantly less in CLWs and PWs. Tear osmolarity was only significantly less in PWs group ( p= 0.041 ) when compared to the non wearers. Other measurements were not significantly different between groups.

 
Conclusions
 

CL wear is associated with negative changes to the tear film and MG function and morphology. These changes appear to persist even after at least 6-months of CL wear discontinuation.

  
Keywords: 477 contact lens • 526 eyelid  
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×