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Amanpreet Kaur, Thuy Chau, Nandor Jaross; Novel 3-Nanosecond Pulse laser and Diabetic Macular Edema: Changes in Visual Acuity and OCT guided analysis of the FLUID.. Invest. Ophthalmol. Vis. Sci. 2014;55(13):6351.
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To evaluate the effects of Novel 3-Nanosecond Pulse (2RT) laser in the treatment of non-centre involving Diabetic Macular Edema. A quantitative analysis of intraretinal and subretinal fluid guided by Cirrus optical coherence tomography using standard image analysis software and observing the changes in visual acuity.
A retrospective analysis of 28 patients with diabetic macular edema that had been treated with nanopulse laser. The laser spots (400 microns) were applied in a grid pattern, one burn width apart to the retinal areas with edema at an energy setting that produced minimal reaction. Patients were followed up for 6 months. The main parameters analysed were changes in visual acuity and intraretinal fluid (IRF) and subretinal fluid (SRF) as assessed by Optical Coherence Tomography (OCT) using standard image analysis software.
Of the 28 patients (33 eyes) enrolled in the study, the majority were male (78.6%) and the mean age was 59.24 ± 10.55 years. Mean logMAR visual acuity improved from a mean 0.07 logMAR to 0.005 logMAR at 6 months (p > 0.0001). Also, while an initial increase in IRF was seen at 1 month, a significant decrease was achieved in IRF at final follow-up (p > 0.0001). No complications were observed in any of the cases.
Retinal rejuvenation therapy (2RT) is safe and effective in the management of non-center involving diabetic macular edema. It is the first report that measured the effects of 2RT laser on intraretinal and subretinal fluid.
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