April 2014
Volume 55, Issue 13
ARVO Annual Meeting Abstract  |   April 2014
Anti-VEGF treatment of CNVM Secondary to Chronic Central Serous Retinopathy
Author Affiliations & Notes
  • Netan Choudhry
    Herzig Eye Institute, Toronto, ON, Canada
  • Footnotes
    Commercial Relationships Netan Choudhry, None
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Investigative Ophthalmology & Visual Science April 2014, Vol.55, 6383. doi:
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      Netan Choudhry; Anti-VEGF treatment of CNVM Secondary to Chronic Central Serous Retinopathy. Invest. Ophthalmol. Vis. Sci. 2014;55(13):6383.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: The purpose of this study was to examine the efficacyof intravitreal Anti-VEGF therapy on the treatment of choroidal neovascular membranes secondary to chronic central serous retinopathy.

Methods: A retrospective review of 5 eyes presenting with chronic central serous retinopathy treated with monthly anti-VEGF 0.5mg (bevacizumab or ranibizumab). Patients underwent baseline fluorescein angiography, OCT with clinical examination. At each monthly visit patient BCVA was measured in conjunction with OCT to measure response. Follow-up time ranged from 3-12 months.

Results: All patient presented with subretinal hemorrhage and leakage on fluorescein angiography upon presentation. Mean visual acuity improvement after 3 months of treatment was + 10 letters and 12 letters at 6 months. All eyes demonstrated improvement of OCT features with complete resolution of subretinal fluid in all eyes by 6 months. Intraretinal cystic fluid and shallow PED"s were present in 4 eyes at 6 months.

Conclusions: Intravitreal Anti-VEGF therapy demonstrated improvement in best-corrected ETDRS visual acuity in all patients and OCT abnormalities, particularly subretinal fluid. Intravitreal Anti-VEGF therapy is an effective treatment for choroidal neovascular membranes secondary to Chronic Central Serous Retinopathy.

Keywords: 453 choroid: neovascularization  

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