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Ines Pereira Marques, Maria Luz Cachulo, Inês Laíns, João Figueira, Conceição Lobo, Sandrina Nunes, Miguel Costa, Vitor Rodrigues, Rufino Silva; Prevalence of Age-related Macular Degeneration in Portugal: the Coimbra Eye Study - Report 1. Invest. Ophthalmol. Vis. Sci. 2014;55(13):651.
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To evaluate the age and gender-specific prevalence of early and late age-related macular degeneration (AMD) in a Portuguese population-based sample.
All patients older than 55 years old of a Portuguese primary health-care unit were invited to participate. Responders underwent complete ophthalmic examination and fundus imaging. AMD and age-related maculopathy (ARM) were defined according to the International ARM Epidemiological Study Group Classification. An innovative semi-automated software (Retmarker AMD Research, Critical Health, SA, Portugal) was used. The age and gender adjusted prevalences for ARM and for neovascular and atrophic forms of AMD were calculated.
Of the 4370 eligible subjects, 3000 participants were included (68,6% response rate) and 2975 were included in the analysis with a mean age of 68.9 ± 8.7 years. The overall prevalence of early and late AMD was 17.71% and 0.67% respectively. Neovascular and atrophic AMD accounted for 0.42% and 0.29% of individuals, respectively. The highest prevalence of advanced AMD was among those aged ≥75 years (1.23% for NV-AMD; 0.66% for GA). Over 82% of the study population showed no features of ARM, or only drusen <63 µm.
To our knowledge, this is the first epidemiologic study of AMD in a Portuguese population. The prevalence of early form in this population-based Portuguese sample was similar to that observed in other large-scale population-based studies. However, the prevalence of late AMD was lower than found in similar studies.
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