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Yi Pang, Megan Allen, Jushua Robinson, Kelly A Frantz, Sandra S Block; Contrast Sensitivity of Amblyopic Eyes in Children with Myopic Anisometropia. Invest. Ophthalmol. Vis. Sci. 2014;55(13):796.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate contrast sensitivity (CS) of amblyopic eyes in children with myopic anisometropia.
Twenty amblyopic children with myopic anisometropia and 16 control subjects with high myopia were recruited. Linear sine-wave grating charts (M&S Technologies, Chicago, IL) of 1.5, 3, 6, 12, and 18 cycles per degree (cpd) were presented to the amblyopic, fellow, and control eyes. Only the data from the right eye of control subjects were used for analysis. One-way analysis of variance with post hoc (Gabriel’s) multiple comparison test was used to compare LogCS of the amblyopic, fellow, and control eyes. Pearson correlation was performed to test the relationships between visual acuity (VA) and LogCS of the amblyopic eyes.
VA of the amblyopic eyes ranged from 20/32 to 20/320. The average amount of myopia in the amblyopic eyes was -10.46 D (range: -5 to -18.25 D). The average amount of myopia in the right eye of control subjects was -8.61 D (range: -6.25 to -13 D). The mean LogCS in the 3 groups (amblyopic, fellow, and control eyes) is listed in Table 1. A statistically significant difference was found in LogCS among the 3 groups (Table 1). Post hoc analysis identified a significant difference in LogCS between amblyopic and fellow eyes as well as between amblyopic and control eyes but not between control and fellow eyes. LogMAR VA in the amblyopic eyes had statistically significant correlations with LogCS at 1.5, 3, 6, and 12 cpd but not with LogCS at 18 cpd.
Contrast sensitivity of amblyopic eyes in children with myopic anisometropia was statistically significantly lower than that of both fellow eyes and control eyes. There was no difference in CS between the fellow eyes of children with myopic anisometropia and the control eyes of normal subjects.
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