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Michael O'Gallagher, Mark R Wilkins; Impact of pre-cutting DSAEK tissue on clinical outcomes. Invest. Ophthalmol. Vis. Sci. 2014;55(13):878.
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The use of pre-cut tissue has many advantages in Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK). Not cutting tissue in theater can present challenges for surgeons who may have concerns over the quality of the cut made in the eye bank. Our large, multi-surgeon training unit recently changed from theater-cut to pre-cut tissue and this study aims to identify any increase in complication rates associated with the use of pre-cut tissue.
A retrospective case note review was carried out. The last 30 patients who received theater-cut tissue and the first 30 who received pre-cut tissue were included. The rates of dislocation requiring refloat and primary graft failure within the first post-operative month were calculated.
Theater-cut tissue had a refloat rate of 27% and a primary graft failure rate of 13%, compared to 23% and 17% respectively for pre-cut tissue. There was no significant difference in these rates.
In this study, the use of pre-cut tissue was not associated with an increase in graft dislocations or primary graft failure. This is in keeping with findings reported in the literature.
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