Abstract
Purpose:
To evaluate endothelial cell loss and graft failure rate after Descemet’s stripping automated endothelial keratoplasty (DSAEK) for corneal edema associated with endothelial dysfunction in eyes with glaucoma drainage devices.
Methods:
A retrospective review of 20 cases performed by a single surgeon (S.B.H) on 17 eyes. Outcome measures included endothelial cell loss and graft failure.
Results:
With a mean follow-up of 29.7 ± 17.1 months, endothelial cell loss was 49% ± 17% at postoperative month 3, 60% ± 16% at month 6, 62% ± 20% at month 12, and 72% ± 18% at month 18. The rate of graft failure was 35%, with most of these eyes requiring repeat endothelial keratoplasty or penetrating keratoplasty.
Conclusions:
DSAEK in eyes with corneal edema secondary to endothelial dysfunction in the presence of glaucoma drainage devices is a successful procedure for visual rehabilitation. The incidences of intermediate term endothelial cell loss and graft failure are significant.
Keywords: 481 cornea: endothelium •
741 transplantation