April 2014
Volume 55, Issue 13
ARVO Annual Meeting Abstract  |   April 2014
Impact of Glaucoma Drainage Device Position on DSAEK Outcomes
Author Affiliations & Notes
  • Jonathan B Greene
    Ophthalmology, University of MIchigan, Ann Arbor, MI
  • Brittany Noble
    Ophthalmology, University of MIchigan, Ann Arbor, MI
  • Denise John
    Ophthalmology, University of MIchigan, Ann Arbor, MI
  • Roni M Shtein
    Ophthalmology, University of MIchigan, Ann Arbor, MI
  • Footnotes
    Commercial Relationships Jonathan Greene, None; Brittany Noble, None; Denise John, None; Roni Shtein, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 895. doi:
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      Jonathan B Greene, Brittany Noble, Denise John, Roni M Shtein; Impact of Glaucoma Drainage Device Position on DSAEK Outcomes. Invest. Ophthalmol. Vis. Sci. 2014;55(13):895.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: To evaluate the impact of glaucoma drainage device (GDD) tube location on outcomes of DSAEK.

Methods: Retrospective review of 24 consecutive DSAEK cases in patients with an anterior chamber (AC) or pars plana (PP) GDD from 2008-2012. Surgical procedures, graft dislocation, rejection, failure, intraocular pressure (IOP) control and other complications were recorded.

Results: Mean postoperative follow-up in AC (n=16) and PP (n=8) groups was 15 and 23 months, respectively. Rates of graft dislocation were similar at 31 and 25%, respectively. Graft failure rate was increased in the AC group (50% vs. 12.5%), but not statistically significant. Time to failure was significantly shorter in the PP group (5.4 vs. 17 months, p<0.0005). There was no significant difference in pre- or post-operative IOP between the groups. No major retinal complications were encountered in the PP group, though 2 patients developed hypotony.

Conclusions: Pars plana positioning of a GDD can safely control IOP in DSAEK. Decreased graft failure rate in the PP group may reflect a decrease in tube-related endothelial cell trauma. Further investigation into the safety of PP tube placement in patients with concern of corneal complications of an AC positioned GDD is warranted.

Keywords: 481 cornea: endothelium • 479 cornea: clinical science • 568 intraocular pressure  

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