A total of 114 consecutive patients presenting to the retina department at Narayana Nethralaya, Bangalore, diagnosed with RP, cone dystrophy, or Stargardt disease were enrolled in the study. The diagnosis of these conditions was made based on the presentation, clinical features, and electrophysiological examination. A detailed history was taken for every patient and patients with any cardiovascular disease, diabetes, hypertension, or history of migraine or using any ocular or systemic medications were excluded. The study followed the tenets of the Declaration of Helsinki. The ethics committee and institutional review board of Narayana Nethralaya approved the study. All patients provided written consent for the study.
All patients underwent a complete ophthalmic examination. These included measurement of the best-corrected visual acuity, anterior segment examination, measurement of the IOPs, and a fundus examination. All underwent fundus photography, spectral-domain optical coherence tomography (SD-OCT), and full-field ERG. Patients younger than 18 years, smokers, and those with a previous history of trauma, nystagmus, and poor media clarity were excluded from the study.
This article summarizes the oximetry findings; the SD-OCT and ERG findings were used only for confirmation of diagnosis. They have not been included, as it would confound the reader with too much information.