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Makoto Inoue, Naoko Matsuki, Yuji Itoh, Toshiyuki Nagamoto, Akito Hirakata; Higher-order aberrations of intraocular lens with intrascleral fixation. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):1072.
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To determine the higher-order aberrations (HOAs) of intraocular lenses (IOLs) with an intrascleral fixation technique.
A computer-aided design system was used to calculate the length of an IOL when it was fixed in the sclera 2 mm posterior to the limbus in a Gullstrand eye model. An acrylic single-piece (SA60AT; Alcon) or 2 three-piece IOLs (VA-60BBR; HOYA, X-60; Santen) was fixed at a length of 13, 14, 15, and 16 mm length. A wavefront analyzer (LAMBDA-X) was used to measure the HOAs within the central 3.0 or 5.2 mm optic diameter.
The length of the IOL with the intrascleral fixation was calculated to be 13.9 to 14.9 mm in the eye model. The astigmatic aberration of the 3-piece VA-60BBR and X-60 IOLs within the central 5.2 mm was significantly greater with an extension of the IOLs (both P<0.001) but not that of the single-piece SA60AT IOL. The coma aberration of the VA-60BBR IOL within the central 5.2 mm increased significantly with an increase in the extension (P =0.001) but not that of the SA60AT and X-60 IOLs. The astigmatic and coma aberrations within the central 5.2 mm were significantly greater than that within the central 3.0 mm for all IOLs. The cylindrical power increased up to 0.034 to 0.082 D with extensions from 13 to 16 mm.
When three-piece IOLs are greatly extended for intrascleral fixation, the astigmatic and coma aberrations increase but the range of changes is not clinically relevant to patients.
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