June 2015
Volume 56, Issue 7
ARVO Annual Meeting Abstract  |   June 2015
Evaluation on the cause of keratitis underwent therapeutic keratoplasty
Author Affiliations & Notes
  • Yusuke Saeki
    Fukuoka University, Fukuoka, Japan
  • Jane Yuh-Huey Huang
    Fukuoka University, Fukuoka, Japan
  • Tomoko Tsukahara
    Fukuoka University, Fukuoka, Japan
  • Eiichi Uchio
    Fukuoka University, Fukuoka, Japan
  • Footnotes
    Commercial Relationships Yusuke Saeki, None; Jane Huang, None; Tomoko Tsukahara, None; Eiichi Uchio, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 1547. doi:
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      Yusuke Saeki, Jane Yuh-Huey Huang, Tomoko Tsukahara, Eiichi Uchio; Evaluation on the cause of keratitis underwent therapeutic keratoplasty. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):1547.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: To examine the cause of infectious keratitis treated by therapeutic keratoplasty.

Methods: The study comprised of 36 eyes (35 patients), all diagnosed with infectious keratitis, and all had undergone initial therapeutic keratoplasty at Fukuoka University Hospital between April 2005 to December 2013. The eyes were evaluated with regard to the causative disease, corneal perforation at first visit, selected keratoplasty, type of donor cornea, and visual prognosis retrospectively.

Results: The causative diseases included keratomycosis (14 eyes), herpetic keratitis (8), bacterial corneal ulcer (3), acanthamoeba kratitis (3), and unknown (7). Corneal perforation was observed in 19 eyes (52.8%) at the first visit. Lamellar keratoplasty was performed in 26 eyes (72.2%) and penetrating keratoplasty in 10 eyes. Preserved frozen corneal buttons (19), fresh corneal buttons (17): eyebank (10), and imported (7), were used as the doner cornea. Visual acuity of 10/100 or above was achieved in 19 eyes (52.8%).

Conclusions: Keratomycosis was the most common cause of infectious keratitis in this study. Therapeutic keratoplasty was effective for severe cases with corneal perforations.


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