Abstract
Purpose:
The aim of this study was to assess the quality of vision of corneal transplanted patients by DSAEK (descemet stripping automated endothelial keratoplasty) for advanced endothelial dysfunction. Clinical data, analysis of the high order aberrations and vision-related quality of life questionnaire were analysed.
Methods:
This is a prospective study of 40 DSAEK 36 patients suffering from corneal decompensation of endothelial origin performed at Regional Hospital Center of Metz. In addition to the analysis of general clinical settings, high order aberrations were measured by Scheimpflug camera one year after surgery. Quality of life related to vision was evaluated before and after surgery using the questionnaire of the National Eye Institute Visual Function Questionnaire-25 (NEIVFQ25).
Results:
The gain line average was 7.11 ± 4.8 Logmar. For HOA, the root mean square (RMS) at 4 mm were 1.59 ± 1,17μm, 1 and 1.22 ± ± 0,9μm 1,12μm respectively for total corneal and anterior and posterior corneal surfaces. A 6 mm, the RMS was 1.84 ± 1,02μm, ± 1.54 and 1.36 ± 1,32μm 1,45μm respectively for the total cornea, anterior and posterior sides. There was a weak correlation between the gain line and the following aberrations: RMS total 4mm (r = 0.38) and posterior RMS to 4 mm (r = 0.40). The global NEIVFQ25 score was 64.5 ± 5.2 before surgery and 75, 8 ± 7.1 after. The following dimensions of the questionnaire NEIVFQ25 were significantly improved by surgery (p <0.05): global vision, near vision, distance vision, eye pain, role difficulties, dependency, social function and mental health.
Conclusions:
The DSAEK surgery generates higher order aberrations weakly correlated to the gain line of visual acuity. It significantly improves the visual acuity and the quality of life related to vision.