Abstract
Purpose:
To identify clinical characteristics associated with poor visual acuity in central serous chorioretinopathy.
Methods:
All charts coded with a diagnosis of central serous chorioretinopathy between December 1, 2001 and September 31, 2013 were reviewed to confirm the diagnosis. Those with a confirmed diagnosis and at least two office visits over a minimum one month follow-up period were included, and the subjects’ charts were reviewed retrospectively. Multivariate logistic regression analyses were performed to assess the relationship between several clinical characteristics and final visual acuity.
Results:
353 subjects were confirmed to have central serous chorioretinopathy. Of these, 258 had a minimum of two clinical assessments and adequate follow-up. Multivariate analysis showed that the following clinical factors were significantly associated with worse final visual acuity: older age at diagnosis, a history of treatment with photodynamic therapy, choroidal neovascularization, hypertension, and a history of either prostate cancer or benign prostatic hypertrophy. Diabetes mellitus was associated with better final visual acuity. In an a subgroup analysis of 151 subjects with at least one year of follow-up, the following factors were significantly associated with worsening of visual acuity over the study period: choroidal neovascularization, use of a psychiatric medication at presentation, hypertension, and gastroesophageal reflux disease.
Conclusions:
Poor visual outcomes in central serous chorioretinopathy are associated with older age at diagnosis, choroidal neovascularization, hypertension, and a history of prostate disease. Several clinical characteristics that have been identified as risk factors for developing central serous also appear to be associated with worse visual outcomes.