June 2015
Volume 56, Issue 7
ARVO Annual Meeting Abstract  |   June 2015
Central Serous Chorioretinopathy: Clinical Characteristics Associated with Visual Outcomes
Author Affiliations & Notes
  • Benjamin Nicholson
    Mayo Clinic, Byron, MN
  • Amrou Ali Idris
    Mayo Clinic, Byron, MN
  • Alan D Marmorstein
    Mayo Clinic, Byron, MN
  • Sophie J Bakri
    Mayo Clinic, Byron, MN
  • Footnotes
    Commercial Relationships Benjamin Nicholson, None; Amrou Ali Idris, None; Alan Marmorstein, None; Sophie Bakri, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 1796. doi:
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      Benjamin Nicholson, Amrou Ali Idris, Alan D Marmorstein, Sophie J Bakri; Central Serous Chorioretinopathy: Clinical Characteristics Associated with Visual Outcomes. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):1796.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: To identify clinical characteristics associated with poor visual acuity in central serous chorioretinopathy.

Methods: All charts coded with a diagnosis of central serous chorioretinopathy between December 1, 2001 and September 31, 2013 were reviewed to confirm the diagnosis. Those with a confirmed diagnosis and at least two office visits over a minimum one month follow-up period were included, and the subjects’ charts were reviewed retrospectively. Multivariate logistic regression analyses were performed to assess the relationship between several clinical characteristics and final visual acuity.

Results: 353 subjects were confirmed to have central serous chorioretinopathy. Of these, 258 had a minimum of two clinical assessments and adequate follow-up. Multivariate analysis showed that the following clinical factors were significantly associated with worse final visual acuity: older age at diagnosis, a history of treatment with photodynamic therapy, choroidal neovascularization, hypertension, and a history of either prostate cancer or benign prostatic hypertrophy. Diabetes mellitus was associated with better final visual acuity. In an a subgroup analysis of 151 subjects with at least one year of follow-up, the following factors were significantly associated with worsening of visual acuity over the study period: choroidal neovascularization, use of a psychiatric medication at presentation, hypertension, and gastroesophageal reflux disease.

Conclusions: Poor visual outcomes in central serous chorioretinopathy are associated with older age at diagnosis, choroidal neovascularization, hypertension, and a history of prostate disease. Several clinical characteristics that have been identified as risk factors for developing central serous also appear to be associated with worse visual outcomes.


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